Thymidine is a pyrimidine 2'-deoxyribonucleoside having thymine as the nucleobase.
Definition
Thymidine is a pyrimidine 2'-deoxyribonucleoside having thymine as the nucleobase. It has a role as a metabolite, a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is functionally related to a thymine. It is an enantiomer of a telbivudine.
Source: PubChem
US FDA substance register · UNII VC2W18DGKR · registered name Doxribtimine · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name チミジン: 本品は、次の化学式で表される複素環式化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 50-89-5
- EC No.EU chemical inventory number
- 200-070-4
- DTXSIDUS EPA chemical ID
- DTXSID5023661
- DTXCIDUS EPA compound ID
- DTXCID703661
- IUPAC
- Thymidine
- Molecular formula
- C10H14N2O5
- Molecular weight
- 242.231 g/mol
Measured properties
- Appearance
- Solid, [Merck Index] White odorless powder, [Alfa Aesar MSDS] · Solid
- Melting point
- 187-189
- Solubility
- 73.5 mg/mL · Water 50 (mg/mL)
- Stability
- Solution: A 1% solution of thymidine in water, kept at room temperature, is stable for at least 24 hours (HPLC).
- Colour
- white
- Odour
- odourless
- pH
- 9.65
- Melting/freezing point
- 182~184 ℃
- Vapour pressure
- 14 ㎜Hg
- Water solubility
- 7960 g/100㎖ (Soluble)
- Relative density
- (0.98681 - 0.99821 g/cm3)
- n-Octanol/water partition coefficient (Kow)
- -0.93
- Molecular weight
- 242.23
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
Source: US EPA CompTox dashboard
Related literature
- Expression of Thymidine Phosphorylase in Lymph Nodes Involved with Mycosis Fungoides and Sézary Syndrome · 2011
- Immunofluorescent Detection of Two Thymidine Analogues (CldU and IdU) in Primary Tissue · 2010
- Mitochondrial DNA Depletion and Thymidine Phosphate Pool Dynamics in a Cellular Model of Mitochondrial Neurogastrointestinal Encephalomyopathy* · 2006
- Phage display of ScFv peptides recognizing the thymidine(6-4)thymidine photoproduct. · 2000
- Thymidine phosphorylase is angiogenic and promotes tumor growth. · 1995
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese