2,6-diaminotoluene is a diamine that is toluene in which both of the hydrogens ortho- to the methyl group are replaced by amino groups.
Definition
2,6-diaminotoluene is a diamine that is toluene in which both of the hydrogens ortho- to the methyl group are replaced by amino groups. It has a role as a mutagen. It is a diamine and a primary amino compound. It derives from a hydride of a toluene.
Source: PubChem
US FDA substance register · UNII H838Q10551 · registered name TOLUENE-2,6-DIAMINE · single chemical substance
Toluene-2,6-Diamine is the substituted aromatic amine that conforms to the formula:
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea · Taiwan · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · Health Canada Cosmetic Ingredient Hotlist · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
EU Cosmetics Regulation, Annex II (prohibited substances), entry 413
Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics
Restriction II/413
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 823-40-5
- EC No.EU chemical inventory number
- 212-513-9
- DTXSIDUS EPA chemical ID
- DTXSID4027319
- DTXCIDUS EPA compound ID
- DTXCID207319
- IUPAC
- 2-Methylbenzene-1,3-diamine
- Molecular formula
- C7H10N2
- Molecular weight
- 122.171 g/mol
Measured properties
- Appearance
- 2,6-diaminotoluene is a colorless prisms (from water). (NTP, 1992) · Other Solid
- Boiling point
- 289 °C
- Melting point
- 223 °F (NTP, 1992) · 106 °C
- Solubility
- Soluble (NTP, 1992) · Soluble in water, ethanol, benzene
- Colour
- colourless
- Melting/freezing point
- 106 ℃
- Initial boiling point and range
- 289 ℃
- Flash point
- 148 ℃
- Vapour pressure
- 0.00246 ㎜Hg (at 25℃)
- Water solubility
- 72500 ㎎/ℓ (at 25℃)
- n-Octanol/water partition coefficient (Kow)
- 0.16
- Molecular weight
- 122.17
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Intermediate1
- Dye1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Skin Sens. 1
Skin Sensitization · Authoritative - Category 2
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Category 2
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
Linked databases 22
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- Health Canada Cosmetic Ingredient Hotlist
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- Taiwan FDA cosmetic ingredients
- Tlooto literature search
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata