Definition
US FDA substance register · UNII OE7HJ54P5C · registered name 3,4-DIAMINOTOLUENE · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · China · European Union · South Korea · Taiwan · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)
Korea’s toxic-substance GHS classification: Danger · H302 (category 4) · H312 (category 4) · H341 (category 2) · +5 more
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1313
Restriction II/1313
Source: EU CosIng ingredient list
Reviewed by CIR: Final Amended Report of the Safety Assessment of Toluene-2,5-Diamine, Toluene-2,5-Diamine Sulfate and Toluene-3,5-Diamine as Used in Cosmetics
Reviewed by CIR: Final Report on the Safety Assessment of Toluene-2,5-Diamine, Toluene-2,5-Diamine Sulfate, and Toluene-3,4-Diamine
CIR reviewed this ingredient and flagged its status as: Insufficient data ingredients with no uses reported to FDA's Voluntary Cosmetic Registration Program (VCRP) (insufficient data or use not supported — CIR's own classification, not a full safety-as-used conclusion).
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 496-72-0
- EC No.EU chemical inventory number
- 207-826-2
- DTXSIDUS EPA chemical ID
- DTXSID9024930
- DTXCIDUS EPA compound ID
- DTXCID104930
- IUPAC
- 4-Methylbenzene-1,2-diamine
- Molecular formula
- C7H10N2
- Molecular weight
- 122.171 g/mol
Measured properties
- Appearance
- solid
- pH
- 8.7 (100 g/ℓ, 20℃)
- Melting/freezing point
- 80~90 ℃
- Initial boiling point and range
- 265 ℃
- n-Octanol/water partition coefficient (Kow)
- 0.66
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Dye1
- Intermediate1
Source: US EPA CompTox dashboard
Related literature
Linked databases 21
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- Taiwan FDA cosmetic ingredients
- Tlooto literature search 2
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3 4
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata