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Ingredients

Ingredient Dictionary

TRIACETIN

Triacetin is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol.

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 2 list it before the 1% line and 14 after it (usually 1% or less).

Products using this ingredient

12 of 16 confirmed · likeliest to carry enough first · See all 16

Definition

Triacetin is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol. It has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections. It has a role as a solvent, an adjuvant, a fuel additive, a food emulsifier, a plant metabolite, a food humectant, a food additive carrier and an antifungal drug. It is functionally related to an acetic acid.

Source: PubChem

US FDA substance register · UNII XHX3C3X673 · registered name Triacetin · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps a film flexiblePLASTICISERLeaves a thin film where appliedFILM FORMINGBase that dissolves other ingredientsSOLVENTInhibits microbial growthANTIMICROBIALListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCE

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Triacetin

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Triacetin

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name トリアセチン: 本品は、酢酸(*)とグリセリン(*)のトリエステルであり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

TRIACETININCI트라이아세틴Korean label name (MFDS standard)1,2,3-Propanetriol, triacetateSynonymトリアセチンJapanese labelling name
CAS No.chemical registry number
102-76-1
EC No.EU chemical inventory number
203-051-9
DTXSIDUS EPA chemical ID
DTXSID3026691
DTXCIDUS EPA compound ID
DTXCID906691
IUPAC
Propane-1,2,3-triyl triacetate
Molecular formula
C9H14O6
Molecular weight
218.205 g/mol

Measured properties

Appearance
Liquid, CBI · Colourless, somewhat oily liquid having a slightly fatty odour
Odour
Slightly fatty odor · Slightly fruity or fatty odor
Boiling point
258-259 °C · 258.00 to 260.00 °C. @ 760.00 mm Hg
Melting point
-78 °C · 3 °C
Solubility
In water, 52,130 mg/L at 24.5 °C · In water, 58,000 mg/L at 25 °C
Density
1.1583 g/cu cm at 20 °C · Bulk density: 9.7 lb/gal
Stability
Chemical stability: Stable under recommended storage conditions. · Stable in usual industrial conditions.
Colour
colourless
Melting/freezing point
4 ℃
Initial boiling point and range
258 ℃
Flash point
138 ℃
Upper/lower flammability or explosive limits
7.7 / 1.1 %
Vapour pressure
0.00248 ㎜Hg (at 25℃)
Water solubility
58000 ㎎/ℓ
Vapour density
7.5
Relative density
1.16
n-Octanol/water partition coefficient (Kow)
0.25
Auto-ignition temperature
433 ℃
Molecular weight
218.21

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 86 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Plasticizer17
  • Fragrance15
  • Solvent11
  • Flavouring and nutrient10
  • Humectant5
  • Processing aids not otherwise specified4
  • Biocide3
  • Pharmaceutical (EPA)3
11 other uses
  • Fuel agents3
  • Soil amendments2
  • Surface modifier2
  • Deodorizer2
  • Film former2
  • Surfactant (surface active agent)2
  • Intermediate1
  • Stabilizing agent1
  • Chemical reaction regulator1
  • Propellants, non-motive (blowing agents)1
  • Adhesion/cohesion promoter1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to

Source: US EPA CompTox dashboard

Related literature

Linked databases 21