Trioctanoin is a triglyceride obtained by acylation of the three hydroxy groups of glycerol by octanoic acid.
How much products actually contain
No product states its amount yet.
Of the products containing it, 78 list it before the 1% line and 4 after it (usually 1% or less).
Products using this ingredient
12 of 81 confirmed · likeliest to carry enough first · See all 81
M·A·CMAC Studio Radiance Serum-Powered Foundation
M·A·CM·A·C Studio Radiance Serum-Powered™ Foundation - C3.5
M·A·CM·A·C Studio Radiance Serum-Powered™ Foundation - C4
M·A·CM·A·C Studio Radiance Serum-Powered™ Foundation - C4.5
M·A·CM·A·C Studio Radiance Serum-Powered™ Foundation - N11
M·A·CM·A·C Studio Radiance Serum-Powered™ Foundation - N12
M·A·CM·A·C Studio Radiance Serum-Powered™ Foundation - N18
M·A·CM·A·C Studio Radiance Serum-Powered™ Foundation - N32
M·A·CM·A·C Studio Radiance Serum-Powered™ Foundation - NC10
M·A·CM·A·C Studio Radiance Serum-Powered™ Foundation - NC11
M·A·CM·A·C Studio Radiance Serum-Powered™ Foundation - NC11.5
M·A·CM·A·C Studio Radiance Serum-Powered™ Foundation - NC12
Definition
Trioctanoin is a triglyceride obtained by acylation of the three hydroxy groups of glycerol by octanoic acid. Used as an alternative energy source to glucose for patients with mild to moderate Alzheimer's disease. It has a role as an anticonvulsant and a plant metabolite. It is a triglyceride and an octanoate ester.
Source: PubChem
US FDA substance register · UNII 6P92858988 · registered name TRICAPRILIN · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Amended Safety Assessment of Triglycerides as Used in Cosmetics
Reviewed by CIR: Final Report on the Safety Assessment of Trilaurin, Triarachidin, Tribehenin, Tricaprin, Tricaprylin, Trierucin, Triheptanoin, Triheptylundecanoin, Triisononanoin, Triisopalmitin, Triisostearin, Trilinolein, Trimyristin, Trioctanoin, Triolein, Tripalmitin, Tripalmitolein, Triricinolein, Tristearin, Triundecanoin, Glyceryl Triacetyl Hydroxystearate, Glyceryl Triacetyl Ricinoleate, and Glyceryl Stearate Diaceate
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name トリカプリリン: 本品は、カプリル酸とグリセリン(*)のトリエステルであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 538-23-8
- EC No.EU chemical inventory number
- 208-686-5
- DTXSIDUS EPA chemical ID
- DTXSID6021375
- DTXCIDUS EPA compound ID
- DTXCID801375
- IUPAC
- Propane-1,2,3-triyl trioctanoate
- Molecular formula
- C27H50O6
- Molecular weight
- 470.691 g/mol
Measured properties
- Appearance
- Tricaprylin is an odorless viscous clear colorless to amber-brown liquid. (NTP, 1992) · Colorless to amber-brown viscous, odorless liquid, mp = 10 deg C, [NTP] Colorless to light yellow odorless liquid, [Acros Organics MSDS]
- Boiling point
- 451.6 °F at 760 mmHg (NTP, 1992) · 233 °C
- Melting point
- 50 °F (NTP, 1992) · 10 °C
- Solubility
- less than 1 mg/mL at 72 °F (NTP, 1992) · Miscible in ethanol, very soluble in ether, benzene, chloroform, ligroin
- Density
- 0.954 at 68 °F (NTP, 1992) - Less dense than water, will float · 0.9540 at 20 °C
- Melting/freezing point
- 5.8 ℃
- Initial boiling point and range
- &, gt, 300 ℃ (1 atm)
- Flash point
- 200.2 ℃
- Vapour pressure
- 0 ㎩ (25℃)
- Water solubility
- 0~0.532 ug/L (20℃, pH: 6.3)
- Relative density
- 0.952
- n-Octanol/water partition coefficient (Kow)
- 9.2 (log Pow)
- Molecular weight
- 470.682
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 17 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner7
- Fragrance4
- Solvent3
- Deodorizer2
- Humectant1
Source: US EPA CompTox dashboard
Related literature
- Neutral Oil-Incorporated Liposomal Nanocarrier for Increased Skin Delivery of Ascorbic Acid · 2023
- Design of Novel Tricaprylin-Incorporated Multi-Layered Liposomal System for Skin Delivery of Ascorbic Acid with Improved Chemical Stability · 2023
- Comparison of adjuvant mechanisms of medium-chain triacylglycerol in a mouse FITC-induced contact hypersensitivity model. · 2023
- Production of thymol nanoemulsions stabilized using Quillaja Saponin as a biosurfactant: Antioxidant activity enhancement. · 2019
- Final Report on the Safety Assessment of Trilaurin, Triarachidin, Tribehenin, Tricaprin, Tricaprylin, Trierucin, Triheptanoin, Triheptylundecanoin, Triisononanoin, Triisopalmitin, Triisostearin, Trilinolein, Trimyristin, Trioctanoin, Triolein, Tripalmitin, Tripalmitolein, Triricinolein, Tristearin, · 2001
Linked databases 21
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English