What is this ingredient?

미국 FDA 물질 등록 · UNII 512641US16 · 등록명 TRICRESOL PHOSPHATE · 혼합물

All ingredients

Ingredient Dictionary

TRICRESYL PHOSPHATE

Definition

US FDA substance register · UNII 512641US16 · registered name TRICRESOL PHOSPHATE · mixture

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps a film flexiblePLASTICISER

Safety & regulatory references

Banned: Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea · United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · Health Canada Cosmetic Ingredient Hotlist · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex II (prohibited substances), entry 277

Source: EU prohibited substances (Annex II)

Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics

Source: Health Canada Cosmetic Ingredient Hotlist

Restriction II/277

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

TRICRESYL PHOSPHATEINCI트라이크레실포스페이트Korean label name (MFDS standard)Phosphoric acid, tris(methylphenyl) esterSynonym

CAS No.chemical registry number: 1330-78-5
EC No.EU chemical inventory number: 215-548-8
DTXSIDUS EPA chemical ID: DTXSID4021391
DTXCIDUS EPA compound ID: DTXCID001778218

Molecular formula: C21H21O4P

Measured properties

Appearance: liquid
Colour: colourless
Odour: odourless
Melting/freezing point: -33 ℃
Initial boiling point and range: 265 ℃
Flash point: &amp, gt, 110 ℃
Upper/lower flammability or explosive limits: - / - %
Vapour pressure: 0.1 ㎜Hg
Water solubility: (0.36 mg/l at 25C)
Vapour density: 12.7
Relative density: 1.2
n-Octanol/water partition coefficient (Kow): 5.11
Viscosity: 29.7 cSt
Molecular weight: 368.39

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 24 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Flame retardant10
Plasticizer8
Lubricating agent6

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

6 skin studies and 3 eye studies are on record.

Classed as moderate1Classed as low2

The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 9 studies

Category 6.3B (Category 3)
Skin Irritation · Read Across
Not classified
Skin Irritation · Screening
Ambiguous
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: For skin irritation, essentially the draize method is quoted. no guideline followed other guideline: 49 CFR 173.240 (a)(1) for dermal corrosion equivalent or similar to
Classification not possible
Skin Sensitization · Screening
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Standard Federal Hazardous Substances Labeling Act tests according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Standard Federal Hazardous Substances Labeling Act tests according to
Classification not possible
Eye Irritation · Screening
Category 6.4A (Category 2A)
Eye Irritation · Read Across