Triethylamine is a tertiary amine that is ammonia in which each hydrogen atom is substituted by an ethyl group.
定義
Triethylamine is a tertiary amine that is ammonia in which each hydrogen atom is substituted by an ethyl group.
出典: PubChem
米国FDA 物質登録 · UNII VOU728O6AY · 登録名 Triethylamine · 単一の化学物質
化粧品での役割
乳化物の分離を防ぐEMULSION STABILISING
安全性・規制情報
韓国の有害物質GHS分類: 危険 · H311 (区分3) · H314 (区分1A) · H331 (区分3) · ほか2件
Restriction III/62 Trialkylamines, trialkanolamines and their salts
出典: EU CosIng 成分リスト
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
別名・識別情報
TRIETHYLAMINEINCIEthanamine, N,N-diethyl-別名
- CAS No.化学物質登録番号
- 121-44-8
- DTXSID米国EPA化学物質番号
- DTXSID3024366
- DTXCID米国EPA化合物番号
- DTXCID204366
- IUPAC
- N,N-Diethylethanamine
- 分子式
- C6H15N
- 分子量
- 101.193 g/mol
測定された物性
- 性状
- Triethylamine appears as a clear colorless liquid with a strong ammonia to fish-like odor. Flash point 20 °F. Vapors irritate the eyes and mucous membranes. Less dense (6.1 lb / gal) than water. Vapors heavier than air. Produces toxic oxides of nitrogen when burned. · Liquid, CBI
- 臭い
- Strong, ammoniacal ordor · Fishy
- 沸点
- 192.7 °F at 760 mmHg (NTP, 1992) · 88.8 °C
- 融点
- -174.5 °F (NTP, 1992) · -114.7 °C
- 溶解性
- Soluble (NTP, 1992) · In water, 6.86X10+4 mg/L at 25 °C
- 密度
- 0.729 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.7275 g/cu cm at 20 °C
- 色
- 無色
- 臭いの閾値
- 1.12 ㎎/㎥
- pH
- 12.5
- 融点・凝固点
- -115 ℃
- 初留点および沸点範囲
- 88~90 ℃ (at 1013 hPa)
- 引火点
- -11 ℃
- 蒸発速度
- 5.6
- 燃焼・爆発範囲の上限/下限
- 8 / 1.2 %
- 蒸気圧
- 7.2 ㎪ (20℃)
- 溶解度
- 17 g/100㎖ (20 ℃ (1), (2))
- 蒸気密度
- 3.5
- 比重
- 0.7
- n-オクタノール/水分配係数（Kow）
- 1.45
- 自然発火温度
- 230 ℃
- 粘度
- 363000 (25℃)
- 分子量
- 101.19
物質そのものを測定した値です。安全保健公団（KOSHA）の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。
出典: PubChem · 韓国安全保健公団 SDS
製品が実際に使っている用途
米国EPAにこの成分を届け出た製品18件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。
- Processing aids not otherwise specified3
- Intermediate3
- Flavouring and nutrient2
- Surfactant (surface active agent)2
- Emulsifier1
- Solvent1
- Pigment1
- Biocide1
その他の用途 4件
- Dispersing agent1
- Surface modifier1
- Cleaning agent1
- pH regulating agent1
出典: 米国EPA CompTox
刺激・感作試験の記録
皮膚試験6件・眼試験4件の記録があります。
刺激が強いと分類1件
試験の結論はおおむね一致しています（100%）。 原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。
試験10件をすべて見る
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: "Development and Validation of an Alternative Dermal Sensitization Test : Mouse Ear Swelling Test (MEST)," by Gad S.C., Dunn B.J., and Dobbs, D.W. in Toxicol. and Appl. Pharmacol, 84, 93-114 (1986) - Category 8.2B (Category 1B)
Skin Irritation · Read Across - Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Category 1
Skin Irritation · Screening - Not classified
Skin Sensitization · Screening - Skin Corr. 1A
Skin Irritation · Authoritative - Category 8.3A (Category 1)
Eye Irritation · Read Across - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Category 1
Eye Irritation · Screening - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
出典: 米国EPA CompTox
関連文献
- Exploring the Antimicrobial and Antitumoral Activities of Naphthoquinone-Grafted Chitosans · 2023
- Triethylammonium 2-(3-Hydroxy-2-oxoindolin-3-yl)-5,5-dimethyl-3-oxocyclohex-1-en-1-olate · 2023
- Encapsulation of Tetraphenylethylene Derivative in Liposome Vesicles as Promising Aggregation-Induced Electrochemiluminescence Emitter for Detection of Human Epidermal Growth Factor Receptor 2. · 2023
- Determination of rhodamine B in water and cosmetics by switchable solvent-based liquid phase microextraction with spectrophotometric determination · 2022
- Simultaneous quantitation of cationic disinfectants by high-performance liquid chromatography on a silica gel column using aqueous eluents · 2020