What is this ingredient?

미국 FDA 물질 등록 · UNII 14I47YJ5EY · 등록명 TRIETHYLENE GLYCOLDIMETHACRYLATE · 단일 화학물질

Ingredient Dictionary

TRIETHYLENE GLYCOL DIMETHACRYLATE

Definition

US FDA substance register · UNII 14I47YJ5EY · registered name TRIETHYLENE GLYCOLDIMETHACRYLATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Cares for nailsNAIL CONDITIONING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Methacrylate Ester Monomers

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Methacrylate Ester Monomers Used in Nail Enhancement Products

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ジメタクリル酸トリエチレングリコール: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

TRIETHYLENE GLYCOL DIMETHACRYLATEINCI트라이에틸렌글라이콜다이메타크릴레이트Korean label name (MFDS standard)2-Propenoic acid, 2-methyl-, 1,2-ethanediylbis(oxy-2,1-ethanediyl) esterSynonymTRIETHYLENEGLYCOL DIMETHACRYLATESynonymジメタクリル酸トリエチレングリコールJapanese labelling name

CAS No.chemical registry number: 109-16-0
EC No.EU chemical inventory number: 203-652-6
DTXSIDUS EPA chemical ID: DTXSID3029607
DTXCIDUS EPA compound ID: DTXCID909607

IUPAC: [(Ethane-1,2-diyl)bis(oxy)ethane-2,1-diyl] bis(2-methylprop-2-enoate)
Molecular formula: C14H22O6
Molecular weight: 286.324 g/mol

Measured properties

Appearance: Liquid · Liquid, [Aldrich MSDS]
Boiling point: 155 °C @ 0.13 kPa
Solubility: > 10% in acetone · > 10% in ethanol
Density: 1.072 at 25 °C · 1.09 @ 20°C
Flash point: &amp, gt, 150 ℃ (c.c.)
Vapour pressure: 0.00094 ㎜Hg (@ 25 ℃, est.)
Water solubility: 3600 ㎎/ℓ (@ 37 ℃)
Vapour density: 9.88
Relative density: 1.092 (@ 20 ℃)
n-Octanol/water partition coefficient (Kow): 1.88
Auto-ignition temperature: 255 ℃ (@ 1025 hPa)
Viscosity: 9.15 cSt (@ 20 ℃)
Molecular weight: 286.33

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 14 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Monomers4
Photosensitive agent2
Adhesion/cohesion promoter2
Intermediate2
Hardener2
Chemical reaction regulator1
Softener and conditioner1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

7 skin studies and 2 eye studies are on record.

Classed as highly irritating1Classed as low2

The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 9 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Appraisal of the safety of chemicals in foods, druge and cosmetics, by the Staft of the Division of Pharmacology, US FDA, skin toxicity according to Draize (1959) according to other guideline: US FHSA Federal regulation: 16 CFR 1500.41 equivalent or similar to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) (1981) and EEC guideline 84/449/EWG, B.4 according to
Sh
Skin Sensitization · Authoritative
SkinSens1
Skin Sensitization · QSAR Predicted
High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) individual approach (adopted 22 July 2010) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) dated May 30, 2008
Category 6.5B (Category 1)
Skin Sensitization · Read Across
Category 6.3A (Category 2)
Skin Irritation · Read Across
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) adopted 24 February 1987 according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to
Category 6.4A (Category 2A)
Eye Irritation · Read Across