Cosmetic roles
Safety & regulatory references
Korea’s toxic-substance GHS classification: Danger · H317 (category 1) · H331 (category 3) · H301 (category 3) · +1 more
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name メタクリル酸トリフルオロエチル: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 352-87-4
- EC No.EU chemical inventory number
- 206-525-3
- DTXSIDUS EPA chemical ID
- DTXSID7059856
- DTXCIDUS EPA compound ID
- DTXCID0038962
- IUPAC
- 2,2,2-Trifluoroethyl 2-methylprop-2-enoate
- Molecular formula
- C6H7F3O2
- Molecular weight
- 168.115 g/mol
Measured properties
- Appearance
- liquid
- Colour
- colourless
- Initial boiling point and range
- 59 ℃
- Vapour pressure
- 2200 ㎩(20 °C)
- Water solubility
- 906 ㎎/ℓ(20 °C)
- Vapour density
- 5.8
- Relative density
- 1.1769 (g/cm³ at 20 °C)
- n-Octanol/water partition coefficient (Kow)
- 2.32
- Molecular weight
- 168.11
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Monomers1
- Film former1
- Intermediate1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 2 eye studies are on record.
The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) adopted 12 May 1981 - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 1981 according to - Category 6.3B (Category 3)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
Linked databases 13
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- Tlooto literature search
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- Wikidata