Triheptanoin is the triester of glycerin and heptanoic acid.
How much products actually contain
No product states its amount yet.
Of the products containing it, 91 list it before the 1% line and 27 after it (usually 1% or less).
Products using this ingredient
12 of 116 confirmed · likeliest to carry enough first · See all 116
VersedVersed Cashmere Color
wet n wildwet n wild Color Icon Multi-Stick | Blue Lah Lah
wet n wildwet n wild Color Icon Multi-Stick | Born To Flirt
wet n wildwet n wild Color Icon Multi-Stick | Burning Bridges
wet n wildwet n wild Color Icon Multi-Stick | Champagne Room
wet n wildwet n wild Color Icon Multi-Stick | Chocolate Cheat Day
wet n wildwet n wild Color Icon Multi-Stick | Keep Diggin'
wet n wildwet n wild Color Icon Multi-Stick | Lavender Bliss
wet n wildwet n wild Color Icon Multi-Stick | Nocturnal Behavior
wet n wildwet n wild Color Icon Multi-Stick | Not So Calm Waters
wet n wildwet n wild Color Icon Multi-Stick | Nudie Culture
wet n wildwet n wild Color Icon Multi-Stick | Pearl
Definition
US FDA substance register · UNII 2P6O7CFW5K · registered name Triheptanoin · single chemical substance
Triheptanoin is the triester of glycerin and heptanoic acid. It conforms to the formula:
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Final Report on the Safety Assessment of Trilaurin, Triarachidin, Tribehenin, Tricaprin, Tricaprylin, Trierucin, Triheptanoin, Triheptylundecanoin, Triisononanoin, Triisopalmitin, Triisostearin, Trilinolein, Trimyristin, Trioctanoin, Triolein, Tripalmitin, Tripalmitolein, Triricinolein, Tristearin, Triundecanoin, Glyceryl Triacetyl Hydroxystearate, Glyceryl Triacetyl Ricinoleate, and Glyceryl Stearate Diaceate
Reviewed by CIR: Amended Safety Assessment of Triglycerides as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name トリヘプタノイン: 本品は、ヘプタン酸とグリセリン（＊）のトリエステルであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 620-67-7
- EC No.EU chemical inventory number
- 210-647-2
- DTXSIDUS EPA chemical ID
- DTXSID40862306
- DTXCIDUS EPA compound ID
- DTXCID40811091
- IUPAC
- Propane-1,2,3-triyl triheptanoate
- Molecular formula
- C24H44O6
- Molecular weight
- 428.61 g/mol
Measured properties
- Appearance
- liquid
- Melting/freezing point
- -25 ℃
- Initial boiling point and range
- 232.4 ℃
- Flash point
- 207 ℃
- Vapour pressure
- 0.00000023 ㎩
- Water solubility
- 4.38 ㎎/ℓ
- Relative density
- 0.964 g/cm³
- n-Octanol/water partition coefficient (Kow)
- 8.86
- Viscosity
- (9.9 mm²/s (static))
- Molecular weight
- 470.3607
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 9 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Viscosity modifier2
- Softener and conditioner2
- Surfactant (surface active agent)2
- Thickening agent1
- Humectant1
- Processing aids not otherwise specified1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) adopted in 1981 according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) adopted in 1987 according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
- Final Report on the Safety Assessment of Trilaurin, Triarachidin, Tribehenin, Tricaprin, Tricaprylin, Trierucin, Triheptanoin, Triheptylundecanoin, Triisononanoin, Triisopalmitin, Triisostearin, Trilinolein, Trimyristin, Trioctanoin, Triolein, Tripalmitin, Tripalmitolein, Triricinolein, Tristearin, · 2001
- Protective and restorative effects of a Commiphora mukul gum resin and triheptanoin preparation on the CCL‐110 skin fibroblast cell line · 2012
- Mitochondrial dysfunction in methylmalonic acidemia: A pilot study using Seahorse technology in peripheral blood · 2025
Linked databases 18
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- Tlooto literature search 2 3
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese