Definition
US FDA substance register · UNII FZ07E4LW2M · registered name TRIMETHOXYCAPRYLYLSILANE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Final Report: Safety Assessment of Alkoxy Alkyl Silanes as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name トリメトキシカプリリルシラン: 本品は、次の化学式で表されるシリコンエーテルである｡
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 3069-40-7
- EC No.EU chemical inventory number
- 221-338-7
- DTXSIDUS EPA chemical ID
- DTXSID80863094
- DTXCIDUS EPA compound ID
- DTXCID70811766
- IUPAC
- Trimethoxy(octyl)silane
- Molecular formula
- C11H26O3Si
- Molecular weight
- 234.411 g/mol
Measured properties
- Appearance
- liquid
- Melting/freezing point
- -66 ℃
- Initial boiling point and range
- 227 ℃
- Flash point
- 95 ℃
- Vapour pressure
- ㎩ (at 25°C)
- Vapour density
- 8.091473938557128
- Relative density
- 0.91 (20°C)
- n-Octanol/water partition coefficient (Kow)
- 3.9
- Auto-ignition temperature
- 225 ℃
- Viscosity
- 2
- Molecular weight
- 234.41
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 11 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Binder3
- Humectant2
- Surface modifier2
- Adhesion/cohesion promoter1
- Chemical reaction regulator1
- Dispersing agent1
- Viscosity modifier1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata