Ingredient Dictionary

TRIMETHYL-1,3-PENTANEDIOL

2,2,4-trimethyl-1,3-Pentanediol is a secondary alcohol.

Definition

2,2,4-trimethyl-1,3-Pentanediol is a secondary alcohol.

Source: PubChem

US FDA substance register · UNII WT1X081P0L · registered name TRIMETHYL-1,3-PENTANEDIOL · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Base that dissolves other ingredientsSOLVENT

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

TRIMETHYL-1,3-PENTANEDIOLINCI트라이메틸-1,3-펜탄다이올Korean label name (MFDS standard)1,3-Pentanediol, 2,2,4-trimethyl-Synonym

CAS No.chemical registry number: 144-19-4
EC No.EU chemical inventory number: 205-619-1
DTXSIDUS EPA chemical ID: DTXSID8027113
DTXCIDUS EPA compound ID: DTXCID407113

IUPAC: 2,2,4-Trimethylpentane-1,3-diol
Molecular formula: C8H18O2
Molecular weight: 146.23 g/mol

Measured properties

Melting/freezing point: 51~52 ℃
Initial boiling point and range: 234 ℃(at 737 mmHg)
Flash point: 110 ℃
Vapour pressure: 0.0045 ㎜Hg (at 25C)
Water solubility: 19000 ㎎/ℓ (at 25C)
Relative density: 0.937 ( at 15C)
n-Octanol/water partition coefficient (Kow): 1.24
Auto-ignition temperature: 346 ℃
Molecular weight: 146.23

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Solvent4
Intermediate1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 1 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Moderate or Mild Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to