What is this ingredient?

미국 FDA 물질 등록 · UNII 72WY3KLB5R · 등록명 2,6,6-TRIMETHYLCYCLOHEX-2-ENE-1,4-DIONE · 단일 화학물질

Ingredient Dictionary

TRIMETHYL-2-CYCLOHEXENE-1,4-DIONE

Definition

US FDA substance register · UNII 72WY3KLB5R · registered name 2,6,6-TRIMETHYLCYCLOHEX-2-ENE-1,4-DIONE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

TRIMETHYL-2-CYCLOHEXENE-1,4-DIONEINCI2-Cyclohexene-1,4-dione, 2,6,6-trimethyl-Synonym

CAS No.chemical registry number: 1125-21-9
EC No.EU chemical inventory number: 214-406-2
DTXSIDUS EPA chemical ID: DTXSID9021685
DTXCIDUS EPA compound ID: DTXCID701685

IUPAC: 2,6,6-Trimethylcyclohex-2-ene-1,4-dione
Molecular formula: C9H12O2
Molecular weight: 152.193 g/mol

Measured properties

Appearance: solid
Odour: slight inherent smell
Melting/freezing point: 24 ℃(1013 hPa)
Initial boiling point and range: 220.7 ℃(at 1013 hPa)
Flash point: 94 ℃(1013 hPa)
Flammability (solid, gas): not flammable
Vapour pressure: 8.96 ㎩ (20 °C)
Water solubility: 20.16 g/100g (25 °C, pH 3.3)
n-Octanol/water partition coefficient (Kow): 1.88 (25°C)
Auto-ignition temperature: 420 ℃ (1013 hPa)
Molecular weight: 152.1904

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance2
Flavouring and nutrient2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 0 eye studies are on record.

Classed as highly irritating1Classed as low1

The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to
High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation)