Trimethylolpropane triacrylate (Technical Grade) can cause cancer according to California Labor Code and the World Health Organization's International Agency for Research on Cancer (IARC).
Definition
Trimethylolpropane triacrylate (Technical Grade) can cause cancer according to California Labor Code and the World Health Organization's International Agency for Research on Cancer (IARC).
Source: PubChem
US FDA substance register · UNII 4B67KGL96S · registered name TRIMETHYLOLPROPANE TRIACRYLATE · single chemical substance
Trimethylolpropane Triacrylate is the triester that conforms to the formula:
Cosmetic roles
Safety & regulatory references
- Banned
- ASEAN · European Union · United Kingdom · 유럽
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)
Korea’s toxic-substance GHS classification: Warning · H319 (category 2) · H317 (category 1) · H412 (category 3) · +2 more
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1718
Restriction II/1718
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name トリアクリル酸トリメチロールプロパン: 本品は、次の化学式で表されるトリエステルである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 15625-89-5
- EC No.EU chemical inventory number
- 239-701-3
- DTXSIDUS EPA chemical ID
- DTXSID0027773
- DTXCIDUS EPA compound ID
- DTXCID407773
- IUPAC
- 2,2-Bis{[(prop-2-enoyl)oxy]methyl}butyl prop-2-enoate (non-preferred name)
- Molecular formula
- C15H20O6
- Molecular weight
- 296.319 g/mol
Measured properties
- Appearance
- Liquid, Dry Powder, CBI · Liquid, [IUCLID] Colorless liquid with a pungent odor, Hygroscopic, Tan or amber in color if impure, [NTP] Clear or yellow liquid with a pungent odor, [Alfa Aesar MSDS]
- Odour
- Acrylic or pungent odor
- Boiling point
- BP: >200 °C at 1 mm Hg
- Solubility
- Insoluble in water
- Density
- 1.11 g/cu cm at 20 °C
- Colour
- colourless
- Melting/freezing point
- -66 ℃
- Initial boiling point and range
- 200 ℃
- Flash point
- 149 ℃(o.c.)
- Vapour pressure
- 0.015 ㎜Hg (20℃)
- Water solubility
- 0.17 g/100㎖
- Vapour density
- 1
- Relative density
- 1.5
- n-Octanol/water partition coefficient (Kow)
- 2.86 (est.)
- Molecular weight
- 296.32
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 17 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent3
- Processing aids not otherwise specified2
- Photosensitive agent2
- Monomers2
- Intermediate2
- Binder2
- Film former1
- Diluent1
2 other uses
- Softener and conditioner1
- Hair fixative (EPA)1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
10 skin studies and 5 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 15 studies
- Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: OECD Guideline No. 404 adopted in July 1992 according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - Skin sensitization - Category 1A
Skin Sensitization · Screening - Category 2
Skin Irritation · Screening - Category 1
Skin Sensitization · Screening - Sh
Skin Sensitization · Authoritative - Category 6.5B (Category 1)
Skin Sensitization · Read Across - Skin Irrit. 2
Skin Irritation · Authoritative - Skin Sens. 1
Skin Sensitization · Authoritative - Category 6.3A (Category 2)
Skin Irritation · Read Across - Ambiguous
eye irritation: in vivo · Screening · other guideline: In general the techniques of tests as published by the FDA af the United States (Fed. Reg. 28 (119), 5582, 1963) and Draize and Kelley (Drug Gosmet. Industr. 71 (1952) 36) are followed. equivalent or similar to - Serious eye damage/eye irritation - Category 2A
Eye Irritation · Screening - Category 2A
Eye Irritation · Screening - Eye Irrit. 2
Eye Irritation · Authoritative - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Curing of UV prints - Assessment of possible toxicological hazard for consumers. · 2021
- Toxicological Assessment of Key Substances in UV-Curable Nail Coatings: HEMA, TMPTA, TPO, HQ, and MEHQ · 2026
- Energy Consumption in the Template Molding Fabrication of Microneedle Patch · 2025
- Single-Step Fabrication of Computationally Designed Microneedles by Continuous Liquid Interface Production · 2016
- Species and gender differences in the carcinogenic activity of trimethylolpropane triacrylate in rats and mice · 2014
Linked databases 27
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- IARC carcinogen classification
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports
- Wikidata
- Wikipedia · English · Chinese