Trimethylolpropane trimethacrylate is a carbonyl compound.
How much products actually contain
No product states its amount yet.
Of the products containing it, 3 list it before the 1% line and 0 after it (usually 1% or less).
Products using this ingredient
3 of 3 confirmed · likeliest to carry enough first
Definition
Trimethylolpropane trimethacrylate is a carbonyl compound.
Source: PubChem
US FDA substance register · UNII S734UC120F · registered name TRIMETHYLOLPROPANE TRIMETHACRYLATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Reviewed by CIR: Methacrylate Ester Monomers
Reviewed by CIR: Final Report on the Safety Assessment of Methacrylate Ester Monomers Used in Nail Enhancement Products
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name トリメタクリル酸トリメチロールプロパン: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 3290-92-4
- EC No.EU chemical inventory number
- 221-950-4
- DTXSIDUS EPA chemical ID
- DTXSID3027530
- DTXCIDUS EPA compound ID
- DTXCID607530
- IUPAC
- 2,2-Bis{[(2-methylprop-2-enoyl)oxy]methyl}butyl 2-methylprop-2-enoate (non-preferred name)
- Molecular formula
- C18H26O6
- Molecular weight
- 338.4 g/mol
Measured properties
- Appearance
- Liquid, Dry Powder · Amber liquid with a musty odor, [AIHA] Yellow viscous liquid, [Alfa Aesar MSDS]
- Melting/freezing point
- -10 ℃
- Flash point
- 174 ℃
- Vapour pressure
- 0.000137 ㎜Hg(at 25 ℃)
- Water solubility
- 13 ㎎/ℓ(at 25 ℃)
- Vapour density
- 11.7
- Relative density
- 1.067 (at 20/4 ℃)
- n-Octanol/water partition coefficient (Kow)
- 4.39
- Decomposition temperature
- 166.3~166.9 ℃
- Molecular weight
- 338
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 22 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Chemical reaction regulator8
- Adhesion/cohesion promoter2
- Film former2
- Intermediate2
- Degradant/impurity (EPA)2
- Photosensitive agent2
- Hardener1
- Polymerization promoter1
2 other uses
- Catalyst1
- Monomers1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 8 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
- Final report of the safety assessment of methacrylate ester monomers used in nail enhancement products. · 2005
- SINTESIS DAN KARAKTERISASI POLIMER BERCETAKAN MOLEKUL TARTRAZIN UNTUK PEMISAHAN WARNA TARTRAZIN PADA KERUPUK · 2025
- Flexible Array of Rigid Porous Microneedles for Bioelectric Skin Patch · 2024
- Coagent Modified Polypropylene Prepared by Reactive Extrusion: A New Look into the Structure-Property Relations of Injection Molded Parts · 2016
- Final Report of the Safety Assessment of Methacrylate Ester Monomers Used in Nail Enhancement Products1 · 2005
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata