Ingredient Dictionary

TRIMETHYLOLPROPANE

Trimethylolpropane is a primary alcohol.

Definition

Trimethylolpropane is a primary alcohol.

Source: PubChem

US FDA substance register · UNII 090GDF4HBD · registered name TRIMETHYLOLPROPANE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Draws in and holds moistureHUMECTANTBase that dissolves other ingredientsSOLVENT

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name トリメチロールプロパン: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

TRIMETHYLOLPROPANEINCI트라이메틸올프로판Korean label name (MFDS standard)1,3-Propanediol, 2-ethyl-2-(hydroxymethyl)-SynonymトリメチロールプロパンJapanese labelling name

CAS No.chemical registry number: 77-99-6
EC No.EU chemical inventory number: 201-074-9
DTXSIDUS EPA chemical ID: DTXSID2026448
DTXCIDUS EPA compound ID: DTXCID806448

IUPAC: 2-Ethyl-2-(hydroxymethyl)propane-1,3-diol
Molecular formula: C6H14O3
Molecular weight: 134.175 g/mol

Measured properties

Appearance: Large Crystals, Other Solid, CBI, Dry Powder, Wet Solid, Liquid · Colorless to white hygroscopic solid, [ICSC] White crystalline chunks, [MSDSonline]
Boiling point: 160 °C @ 5 MM HG · 292-297 °C
Melting point: 58 °C
Solubility: SOL IN ALL PROP IN WATER, ALCOHOL, INSOL IN BENZENE, CARBON TETRACHLORIDE · Solubility in water at 20 °C: miscible
Density: 1.084 g/cm³
Melting/freezing point: 58 ℃
Initial boiling point and range: 292~297 ℃
Flash point: 172 ℃(c.c.)
Flammability (solid, gas): combustible
Upper/lower flammability or explosive limits: 11.8 / 2.0 %
Vapour pressure: 0.00002 ㎪ ((15E-5 mmHg) at 25C)
Vapour density: 4.63 (air=1)
Relative density: 1.09
n-Octanol/water partition coefficient (Kow): -0.5
Auto-ignition temperature: 375 ℃
Molecular weight: 134.2

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 30 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Processing aids not otherwise specified10
Solvent4
Pigment4
Monomers3
Humectant2
Chemical reaction regulator2
Intermediate2
Lubricating agent1

2 other uses

Heat stabilizer1
Elasticizer1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 0 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 1 studies

Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)