Triphenyl phosphate is an aryl phosphate resulting from the formal condensation of phosphoric acid with 3 mol eq.
How much products actually contain
No product states its amount yet.
Of the products containing it, 259 list it before the 1% line and 0 after it (usually 1% or less).
Products using this ingredient
12 of 259 confirmed · likeliest to carry enough first · See all 259
Definition
Triphenyl phosphate is an aryl phosphate resulting from the formal condensation of phosphoric acid with 3 mol eq. of phenol. It has a role as a plasticiser and a flame retardant. It is functionally related to a phenol.
Source: PubChem
US FDA substance register · UNII YZE19Z66EA · registered name TRIPHENYL PHOSPHATE · single chemical substance
Triphenyl Phosphate is the organic compound that conforms to the formula:
Cosmetic roles
Safety & regulatory references
- Banned
- European Union
Source: EU Cosmetics Regulation
Korea’s toxic-substance GHS classification: Warning · H410 (category 1) · H400 (category 1)
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1767
Reviewed by CIR: Safety Assessment of Triphenyl Phosphate as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name トリフェニルリン酸: 本品は、リン酸(*)とフェノール(*)とのトリエステルであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 115-86-6
- EC No.EU chemical inventory number
- 204-112-2
- DTXSIDUS EPA chemical ID
- DTXSID1021952
- DTXCIDUS EPA compound ID
- DTXCID201952
- IUPAC
- Triphenyl phosphate
- Molecular formula
- C18H15O4P
- Molecular weight
- 326.288 g/mol
Measured properties
- Appearance
- Triphenyl phosphate appears as colorless crystals. (NTP, 1992) · Other Solid, Dry Powder, CBI, Liquid
- Odour
- Odorless · Phenol-like odor
- Boiling point
- 473 °F at 11 mmHg (NTP, 1992) · BP: 245 °C at 11 mm Hg
- Melting point
- 122 to 124 °F (NTP, 1992) · 49.39 °C
- Solubility
- Insoluble (NTP, 1992) · In water, 1.9 mg/L at 25 °C
- Density
- 1.2055 (NTP, 1992) - Denser than water, will sink · Density: 1.2055 g/cu cm at 50 °C
- Colour
- colourless
- Melting/freezing point
- 49.39 ℃
- Initial boiling point and range
- 370 ℃
- Flash point
- 220 ℃(c.c.)
- Vapour pressure
- 0.000002 ㎜Hg(25℃)
- Water solubility
- 1.9 ㎎/ℓ(25℃)
- Vapour density
- 1.19
- Relative density
- 1.2055 (50℃)
- n-Octanol/water partition coefficient (Kow)
- 4.59
- Molecular weight
- 326.29
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 38 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Flame retardant16
- Plasticizer13
- Processing aids not otherwise specified3
- Binder2
- Lubricating agent2
- Hydraulic fluids2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 4 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not classified
Skin Irritation · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Classification not possible
Skin Sensitization · Screening - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Moderate or Mild Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Category 2B
Eye Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Perinatal triphenyl phosphate exposure induces metabolic dysfunctions through the EGFR/ERK/AKT signaling pathway: Mechanistic in vitro and in vivo studies. · 2023
- SVOCs, VOCs and microbiological contamination in sports facilities, what are people exposed to? · 2026
- Safety Assessment of Triphenyl Phosphate as Used in Cosmetics · 2024
- Green purchase behavior: a preliminary study · 2024
- Triphenyl phosphate-induced pericardial edema in zebrafish embryos is reversible following depuration in clean water · 2023
Linked databases 24
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- EU SCCS safety opinions
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese