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Ingredient Dictionary

TRIPOTASSIUM PHOSPHATE

Tripotassium phosphate is an inorganic potassium salt that is the tripotassium salt of phosphoric acid.

Molecular structure

Definition

Tripotassium phosphate is an inorganic potassium salt that is the tripotassium salt of phosphoric acid. It is an inorganic phosphate salt and an inorganic potassium salt.

Source: PubChem

US FDA substance register · UNII 16D59922JU · registered name POTASSIUM PHOSPHATE, TRIBASIC · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Tripotassium Phosphate is the inorganic salt that conforms to the formula:

Cosmetic roles

Keeps pH steadyBUFFERING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

TRIPOTASSIUM PHOSPHATEINCIPhosphoric acid, tripotassium saltSynonym
CAS No.chemical registry number
7778-53-2
EC No.EU chemical inventory number
231-907-1
DTXSIDUS EPA chemical ID
DTXSID3043994
DTXCIDUS EPA compound ID
DTXCID1023994
IUPAC
Tripotassium phosphate
Molecular formula
K3O4P
Molecular weight
212.265 g/mol

Measured properties

Appearance
Other Solid · Other Solid, Dry Powder, Liquid
Solubility
Freely soluble in water. Insoluble in ethanol
pH
Between 11,5 and 12,3 (1 % solution)
Molecular weight
212.27

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 13 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • pH regulating agent4
  • Corrosion inhibitor2
  • Emulsifier1
  • Thickening agent1
  • Adhesion/cohesion promoter1
  • Ion exchange agent1
  • Processing aids not otherwise specified1
  • Chelating agent1
1 other uses
  • Cleaning agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

7 skin studies and 4 eye studies are on record.

Classed as moderate1Classed as low3

The studies disagree (the most common conclusion covers 25%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 11 studies
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • Classification not possible
    Skin Sensitization · Screening
  • Studies Indicate No Significant Irritation
    skin corrosion: in vitro / ex vivo · Screening · OECD Guideline 439 (In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method) according to EU Method B.46 (In Vitro Skin Irritation: Reconstructed Human Epidermis Model Test) according to
  • Category 1
    Skin Irritation · Screening
  • Skin corrosion/irritation - Category 2
    Skin Irritation · Screening
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · other guideline: No data according to
  • Not likely to be sensitizing
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay)
  • Serious eye damage/eye irritation - Category 1
    Eye Irritation · Screening
  • Corrosive or Irritation Persists for > 21 days
    eye irritation: in vivo · Screening · other guideline: Code of Federal Regulation, Section 1500.42 according to
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across
  • Category 1
    Eye Irritation · Screening

Source: US EPA CompTox dashboard

Related literature

Linked databases 14