Tripotassium phosphate is an inorganic potassium salt that is the tripotassium salt of phosphoric acid.
Definition
Tripotassium phosphate is an inorganic potassium salt that is the tripotassium salt of phosphoric acid. It is an inorganic phosphate salt and an inorganic potassium salt.
Source: PubChem
US FDA substance register · UNII 16D59922JU · registered name POTASSIUM PHOSPHATE, TRIBASIC · single chemical substance
Tripotassium Phosphate is the inorganic salt that conforms to the formula:
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 7778-53-2
- EC No.EU chemical inventory number
- 231-907-1
- DTXSIDUS EPA chemical ID
- DTXSID3043994
- DTXCIDUS EPA compound ID
- DTXCID1023994
- IUPAC
- Tripotassium phosphate
- Molecular formula
- K3O4P
- Molecular weight
- 212.265 g/mol
Measured properties
- Appearance
- Other Solid · Other Solid, Dry Powder, Liquid
- Solubility
- Freely soluble in water. Insoluble in ethanol
- pH
- Between 11,5 and 12,3 (1 % solution)
- Molecular weight
- 212.27
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 13 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- pH regulating agent4
- Corrosion inhibitor2
- Emulsifier1
- Thickening agent1
- Adhesion/cohesion promoter1
- Ion exchange agent1
- Processing aids not otherwise specified1
- Chelating agent1
1 other uses
- Cleaning agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
7 skin studies and 4 eye studies are on record.
The studies disagree (the most common conclusion covers 25%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 11 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Classification not possible
Skin Sensitization · Screening - Studies Indicate No Significant Irritation
skin corrosion: in vitro / ex vivo · Screening · OECD Guideline 439 (In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method) according to EU Method B.46 (In Vitro Skin Irritation: Reconstructed Human Epidermis Model Test) according to - Category 1
Skin Irritation · Screening - Skin corrosion/irritation - Category 2
Skin Irritation · Screening - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: No data according to - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) - Serious eye damage/eye irritation - Category 1
Eye Irritation · Screening - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · other guideline: Code of Federal Regulation, Section 1500.42 according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Category 1
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Lidocaine tripotassium phosphate complex laden microemulsion for prolonged local anaesthesia: In vitro and in vivo studies. · 2019
- Microbicidal activity of tripotassium phosphate and fatty acids toward spoilage and pathogenic bacteria associated with poultry. · 2005
- Bactericidal activity of tripotassium phosphate and potassium oleate on the native flora of poultry skin · 2003
Linked databases 14
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese