Definition
US FDA substance register · UNII 253H13NWCQ · registered name 1,3,5-TRI(4-TERT-BUTYL-2,6-DIMETHYL-3-HYDROXYBENZYL)-1,3,5-TRIAZINE-2,4,6(1H,3H,5H)-TRIONE · single chemical substance
Tris(t-Butyl Hydroxydimethylbenzyl) Isocyanuric Acid is the organic compound that conforms to the formula:
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 40601-76-1
- EC No.EU chemical inventory number
- 254-996-9
- DTXSIDUS EPA chemical ID
- DTXSID8028008
- DTXCIDUS EPA compound ID
- DTXCID008008
- IUPAC
- 1,3,5-Tris[(4-tert-butyl-3-hydroxy-2,6-dimethylphenyl)methyl]-1,3,5-triazinane-2,4,6-trione
- Molecular formula
- C42H57N3O6
- Molecular weight
- 699.933 g/mol
What products actually use it for
What the 28 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Antioxidant23
- Processing aids not otherwise specified2
- Catalyst1
- UV stabilizer1
- Fragrance1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Japanese Ministry of Agriculture, Forestry and Fisheries (JMAFF), 12 Nohsan, Notification No. 8147, April 2011; including the most recent partial revisions according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to EPA OPPTS 870.2500 (Acute Dermal Irritation) according to - SkinIrr2
Skin Irritation · QSAR Predicted - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Japanese Ministry of Agriculture, Forestry and Fisheries (JMAFF), 12 Nohsan, Notification No. 8147, April 2011; including the most recent partial revisions according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to EPA OPPTS 870.2400 (Acute Eye Irritation) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: modified FHSA procedure according to
Source: US EPA CompTox dashboard
Linked databases 11
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese