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Ingredients

Ingredient Dictionary

TRIS(TETRAMETHYLHYDROXYPIPERIDINOL) CITRATE

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 17 list it before the 1% line and 70 after it (usually 1% or less).

Products using this ingredient

12 of 87 confirmed · likeliest to carry enough first · See all 87

Definition

US FDA substance register · UNII 7NW772I64Y · registered name TRIS(TETRAMETHYLHYDROXYPIPERIDINOL) CITRATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Absorbs UV (including to protect the product)UV ABSORBER

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Safety Assessment of Hydroxy Tetramethylpiperidine Oxide and Tris(Tetramethylhydroxypiperidinol)) Citrate as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name クエン酸トリス(テトラメチルヒドロキシピペリジノール): 本品は、次の化学式で表される有機塩である。

Source: JCIA labelling names (Japan)

Names & identifiers

TRIS(TETRAMETHYLHYDROXYPIPERIDINOL) CITRATEINCI트리스(테트라메틸하이드록시피페리딘올)시트레이트Korean label name (MFDS standard)4-piperidinol, 1-hydroxy-2,2,6,6-tetramethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (3:1) (salt)Synonymクエン酸トリス(テトラメチルヒドロキシピペリジノール)Japanese labelling name
CAS No.chemical registry number
220410-74-2
EC No.EU chemical inventory number
429-370-5
DTXSIDUS EPA chemical ID
DTXSID1074387
DTXCIDUS EPA compound ID
DTXCID6036598
IUPAC
2-Hydroxypropane-1,2,3-tricarboxylic acid--2,2,6,6-tetramethylpiperidine-1,4-diol (1/3)
Molecular formula
C33H65N3O13
Molecular weight
711.891 g/mol

What products actually use it for

What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • UV stabilizer2
  • Fragrance2
  • Stabilizing agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) adopted July 17, 1992
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) adopted July 17, 1992 according to
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) adopted February 24, 1987 according to

Source: US EPA CompTox dashboard

Related literature

Linked databases 15