Ingredient Dictionary

TRISILOXANE

Octamethyltrisiloxane is an organosiloxane that is trisiloxane in which all the hydrogens have been replaced by methyl groups.

How much products actually contain

No product states its amount yet.

Of the products containing it, 131 list it before the 1% line and 24 after it (usually 1% or less).

Products using this ingredient

12 of 151 confirmed · likeliest to carry enough first · See all 151

Definition

Octamethyltrisiloxane is an organosiloxane that is trisiloxane in which all the hydrogens have been replaced by methyl groups.

Source: PubChem

US FDA substance register · UNII 9G1ZW13R0G · registered name TRISILOXANE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Removes unwanted foamANTIFOAMINGSkin conditioning not covered aboveSKIN CONDITIONING - MISCELLANEOUS

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name トリシロキサン: 本品は、次の化学式で表される直鎖シロキサンである。

Source: JCIA labelling names (Japan)

Names & identifiers

TRISILOXANEINCI트라이실록세인Korean label name (MFDS standard)Trisiloxane, octamethyl-SynonymトリシロキサンJapanese labelling name

CAS No.chemical registry number: 107-51-7
EC No.EU chemical inventory number: 203-497-4
DTXSIDUS EPA chemical ID: DTXSID9040710
DTXCIDUS EPA compound ID: DTXCID7020710

IUPAC: Octamethyltrisiloxane
Molecular formula: C8H24O2Si3
Molecular weight: 236.533 g/mol

Measured properties

Appearance: liquid
Colour: colourless
Melting/freezing point: 82 ℃
Initial boiling point and range: 153 ℃
Flash point: 29 ℃
Vapour pressure: 3.34 ㎜Hg (National Emergency Management Agency(http://hazmat.nema.go.kr/index.jsp))
Water solubility: 0.034 ㎎/ℓ (25 deg c)
Relative density: 0.82
n-Octanol/water partition coefficient (Kow): 4.8

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Heat transferring agent1
Intermediate1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 1 eye studies are on record.

Classed as low3

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 4 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EPA OPPTS 870.2500 (Acute Dermal Irritation) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation)
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EPA OPPTS 870.2400 (Acute Eye Irritation) according to