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Ingredients

Ingredient Dictionary

TRISODIUM HEDTA

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 0 list it before the 1% line and 14 after it (usually 1% or less).

Products using this ingredient

12 of 14 confirmed · likeliest to carry enough first · See all 14

Definition

US FDA substance register · UNII K3E0U7O8KI · registered name TRISODIUM HEDTA · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Binds metal ions to prevent spoilageCHELATING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: EDTA and Salts

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of EDTA, Calcium Disodium EDTA, Diammonium EDTA, Dipotassium EDTA, Disodium EDTA, HEDTA, TEA-EDTA, Tetrasodium EDTA, Tripotassium EDTA, Trisodium EDTA, and Trisodium HEDTA

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name HEDTA-3Na: 本品は、次の化学式で表されるジアミン誘導体である。

Source: JCIA labelling names (Japan)

Names & identifiers

TRISODIUM HEDTAINCI트라이소듐에이치이디티에이Korean label name (MFDS standard)Glycine, N-[2-[bis(carboxymethyl)amino]ethyl]-N-(2-hydroxyethyl)-, trisodium saltSynonymHEDTA-3NaJapanese labelling name
CAS No.chemical registry number
1330-54-7
CAS No.chemical registry number
139-89-9
EC No.EU chemical inventory number
205-381-9
DTXSIDUS EPA chemical ID
DTXSID9027075
DTXCIDUS EPA compound ID
DTXCID807075
IUPAC
Trisodium N-{2-[bis(carboxylatomethyl)amino]ethyl}-N-(2-hydroxyethyl)glycinate
Molecular formula
C10H15N2Na3O7
Molecular weight
344.206 g/mol

Measured properties

Appearance
solid
Decomposition temperature
288-290 ℃
Molecular weight
344.22

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 15 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Chelating agent6
  • Processing aids not otherwise specified2
  • Ion exchange agent2
  • Stabilizing agent1
  • Intermediate1
  • Preservative1
  • Anti-scaling agent1
  • Soil amendments1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 1 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies
  • SkinSens1
    Skin Sensitization · QSAR Predicted
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across

Source: US EPA CompTox dashboard

Related literature

Linked databases 17