Ingredient Dictionary

TRISODIUM PHOSPHATE

Trisodium phosphate is a sodium phosphate.

How much products actually contain

No product states its amount yet.

Of the products containing it, 0 list it before the 1% line and 8 after it (usually 1% or less).

Products using this ingredient

8 of 8 confirmed · likeliest to carry enough first

Definition

Trisodium phosphate is a sodium phosphate.

Source: PubChem

US FDA substance register · UNII SX01TZO3QZ · registered name SODIUM PHOSPHATE, TRIBASIC, ANHYDROUS · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps pH steadyBUFFERINGBinds metal ions to prevent spoilageCHELATING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Safety Assessment of Phosphoric Acid and Its Salts as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name リン酸３Ｎａ: 本品は、リン酸（＊）の三ナトリウム塩であり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

TRISODIUM PHOSPHATEINCI트라이소듐포스페이트Korean label name (MFDS standard)Phosphoric acid, trisodium saltSynonymリン酸３ＮａJapanese labelling name

CAS No.chemical registry number: 7601-54-9
EC No.EU chemical inventory number: 231-509-8
DTXSIDUS EPA chemical ID: DTXSID2035223
DTXCIDUS EPA compound ID: DTXCID0015223

IUPAC: Trisodium phosphate
Molecular formula: Na3O4P
Molecular weight: 163.939 g/mol

Measured properties

Appearance: Sodium phosphate, tribasic appears as a colorless to white crystalline solid. Noncombustible. · CBI, Large Crystals, Other Solid, Dry Powder, Liquid
Boiling point: The hydrate loses 11 moles of water at 212 °F. (USCG, 1999)
Melting point: 170.06 °F (USCG, 1999) · 170 °F
Solubility: Freely soluble in water. Insoluble in ethanol · Colorless or white crystals. When rapidly heated melts at about 75 °C. Does not lose the last mol of water even on moderate ignition. Specific gravity 1.6. Soluble in 3.5 parts water, 1 part boiling water, insol in alcohol. /Dodecahydrate/
Density: 1.62 at 68 °F (Hydrate) 2.52 anhydrous (USCG, 1999) - Denser than water, will sink · 2.54 g/cu cm
Stability: Rapidly absorbs ... water if exposed to moist atmosphere /Dried sodium phosphate/
pH: Between 11,5 and 12,5 (1 % solution) · The aqueous soln is strongly alkaline. pH of 0.1% soln: 11.5, of 0.5% soln: 11.7, of 1.0% soln: 11.9.
Odour: odourless
Melting/freezing point: 450~1583 ℃
Water solubility: 285 g/ℓ(20℃)
Vapour density: 1.62
Relative density: 2.54 (17.5℃)
n-Octanol/water partition coefficient (Kow): -7.64 (est.)
Decomposition temperature: &amp, gt, 75 ℃
Molecular weight: 163.94

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 53 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Chelating agent13
Cleaning agent7
pH regulating agent6
Flavouring and nutrient3
Emulsifier3
Processing aids not otherwise specified3
Anti-freeze agent2
Softener and conditioner2

12 other uses

Soil amendments2
Lubricating agent2
Anti-caking agent1
Filler1
Humectant1
Biocide1
Anti-scaling agent1
Solids separation (precipitating) agent, not other1
Wetting agent (non-aqueous)1
Pigment1
Surfactant (surface active agent)1
Drier1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

8 skin studies and 5 eye studies are on record.

Classed as highly irritating2Classed as moderate1Classed as low5

The studies disagree (the most common conclusion covers 25%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 13 studies

Classification not possible
Skin Sensitization · Screening
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: FDA revision of the test for primary skin irritants, Part 191, Chapter 1, Title 21. according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Severe Irritation
skin irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labelling Act according to
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay)
Category 8.2C (Category 1C)
Skin Irritation · Read Across
Skin corrosion/irritation - Category 2
Skin Irritation · Screening
Category 1
Skin Irritation · Screening
Severe Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labelling Act" according to
Category 1
Eye Irritation · Screening
Serious eye damage/eye irritation - Category 1
Eye Irritation · Screening
Severe Irritation
eye irritation: in vivo · Screening · EPA OTS 798.4500 (Acute Eye Irritation) according to
Category 8.3A (Category 1)
Eye Irritation · Read Across