Tristearoylglycerol is a triglyceride that is glycerol in which all three hydroxy groups have been formally esterified with stearic acid.
How much products actually contain
No product states its amount yet.
Of the products containing it, 1 list it before the 1% line and 0 after it (usually 1% or less).
Products using this ingredient
1 of 1 confirmed · likeliest to carry enough first
Definition
Tristearoylglycerol is a triglyceride that is glycerol in which all three hydroxy groups have been formally esterified with stearic acid. It has a role as a plant metabolite and a Caenorhabditis elegans metabolite. It is functionally related to an octadecanoic acid.
Source: PubChem
Glycerol tristearate
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Reviewed by CIR: Amended Safety Assessment of Triglycerides as Used in Cosmetics
Reviewed by CIR: Final Report on the Safety Assessment of Trilaurin, Triarachidin, Tribehenin, Tricaprin, Tricaprylin, Trierucin, Triheptanoin, Triheptylundecanoin, Triisononanoin, Triisopalmitin, Triisostearin, Trilinolein, Trimyristin, Trioctanoin, Triolein, Tripalmitin, Tripalmitolein, Triricinolein, Tristearin, Triundecanoin, Glyceryl Triacetyl Hydroxystearate, Glyceryl Triacetyl Ricinoleate, and Glyceryl Stearate Diaceate
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name トリステアリン: 本品は、ステアリン酸（＊）とグリセリン（＊）のトリエステルであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 555-43-1
- EC No.EU chemical inventory number
- 209-097-6
- DTXSIDUS EPA chemical ID
- DTXSID8047503
- DTXCIDUS EPA compound ID
- DTXCID6027503
- IUPAC
- Propane-1,2,3-triyl trioctadecanoate
- Molecular formula
- C57H110O6
- Molecular weight
- 891.501 g/mol
Measured properties
- Appearance
- solid
- Odour
- odourless
- Melting/freezing point
- 71.3 ℃
- Initial boiling point and range
- &, gt, 400 ℃
- Flammability (solid, gas)
- not flammable
- Vapour pressure
- &, lt, 5 ㎩ (20℃)
- Vapour density
- 0.856
- Relative density
- 0.8559 (32964℃)
- n-Octanol/water partition coefficient (Kow)
- &, gt, 8 (log Pow, 22℃)
- Molecular weight
- 891.5
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 19 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Lubricating agent5
- Softener and conditioner3
- Viscosity modifier2
- Processing aids not otherwise specified2
- Surface modifier1
- Humectant1
- Thickening agent1
- Anti-adhesive/cohesive1
3 other uses
- Solvent1
- Emulsifier1
- Surfactant (surface active agent)1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) adopted in 1992 according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) adopted in 1992 according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) adopted in 1992 according to EU Method B.6 (Skin Sensitisation) adopted in 1996 - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) adopted in 1992 according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) adopted in 1992 according to
Source: US EPA CompTox dashboard
Related literature
- Development, characterization, molecular docking, and in vivo skin penetration of coenzyme Q10 nanostructured lipid carriers using tristearin and stearyl alcohol for dermal delivery · 2021
- Lipid nanostructures for antioxidant delivery: a comparative preformulation study · 2019
- Phase behaviour of model triglyceride ternary blends: triolein, tripalmitin and tristearin. · 2022
- Preparation, characterization, and physical stability of cocoa butter and tristearin nanoparticles containing β-carotene · 2020
- Production and Characterization of Nanoparticle Based Hyaluronate Gel Containing Retinyl Palmitate for Wound Healing. · 2018
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese