Trolox is a chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8.
定義
米国FDA 物質登録 · UNII S18UL9710X · 登録名 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID · 単一の化学物質
Trolox is a chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8. A cell-permeable, water-soluble analogue of vitamin E, it is used as a standard for measuring the antioxidant capacity of complex mixtures. It has a role as a ferroptosis inhibitor, an antioxidant, a radical scavenger, a neuroprotective agent and a Wnt signalling inhibitor. It is a chromanol, a monocarboxylic acid and a member of phenols.
出典: PubChem
Trolox is a organic compound.
化粧品での役割
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
別名・識別情報
- CAS No.化学物質登録番号
- 53188-07-1
- DTXSID米国EPA化学物質番号
- DTXSID60866306
- DTXCID米国EPA化合物番号
- DTXCID60220823
- IUPAC
- 6-Hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid
- 分子式
- C14H18O4
- 分子量
- 250.294 g/mol
製品が実際に使っている用途
米国EPAにこの成分を届け出た製品1件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。
- Softener and conditioner1
出典: 米国EPA CompTox
関連文献
- Discovery of Trolox amide derivatives as potent membrane-targeted ferroptosis inhibitors for corneal injury therapy. · 2026
- Trolox derivatives: Synthesis, structure-activity relationship and promote wound healing by regulating oxidative stress and inflammation. · 2024
- Suppression of menthyl anthranilate (UV-A sunscreen)-sensitized singlet oxygen generation by Trolox and , α-tocopherol · 2020
- Scavenging of Retinoid Cation Radicals by Urate, Trolox, and α-, β-, γ-, and δ-Tocopherols · 2019
- Mesoporous silica as a carrier for topical application: the Trolox case study. · 2012