トロメタミン

Tris is a primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group. A compound widely used as a biological buffer substance in the pH range 79; pKa = 8.3 at 20 C; pKa = 7.82 at 37 C. It has a role as a buffer. It is a triol and a primary amino compound. It is a conjugate base of a member of Htris.

出典: PubChem

米国FDA 物質登録 · UNII 023C2WHX2V · 登録名 TROMETHAMINE · 単一の化学物質

出典: 米国FDA 物質識別番号（UNII）

制限・禁止

韓国 · 中国

出典: 韓国食薬処 化粧品規制情報

アルゼンチン · ブラジル

• Maximum concentration permitted at final product : Under maximum secondary amine: 0.5%
• Other limitations and requirements : No use with nitrosating systems. Minimum 99% -Pureza. Maximum -Tenor of secondary amines in raw materials 0.5%. Maximum nitrosamine -Tenor: 50 ug / kg. -Envasar / Nitrite - free store in containers.

ASEAN

• Maximum authorised concentration in the finished cosmetic product : Maximum secondary amine content: 0.5%
• Other limitations and requirements : • Do not use with nitrosating systems • Minimum purity: 99% • Maximum secondary amine content: 0.5% (applies to raw materials) • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers

欧州連合

• Maximum concentration in ready for use preparation : Maximum secondary amine content: 0.5%
• Other : - Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

韓国の有害物質GHS分類なし · 既存化学物質

出典: 韓国 有害物質GHS情報（環境公団）

Restriction III/61

出典: EU CosIng 成分リスト

Reviewed by CIR: Safety Assessment of Tromethamine, Aminomethyl Propanediol and Aminoethyl Propanediol as Used in Cosmetics

出典: 米国CIR 安全性評価