7,9-dihydro-1H-purine-2,6,8(3H)-trione is an oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
How much products actually contain
No product states its amount yet.
Of the products containing it, 4 list it before the 1% line and 25 after it (usually 1% or less).
Products using this ingredient
12 of 29 confirmed · likeliest to carry enough first · See all 29
CREMORLABT.E.N Cremor® Skin Renewal Cream
CREMORLABCremorlab T.E.N Cremor® Skin Renewal Cream
CREMORLABMacro Serum Mask® 3D Renewing 4 Sheets
CREMORLABCremorlab Macro Serum Mask® 3D Renewing 4 Sheets
AESTURAAtoBarrier 365 Hydro Essence 200ml
AESTURAAtoBarrier 365 Hydro Essence
AYUNCHEPro The Bond
FATIONGlucose Hydro Mask 20ml
FATIONGlucose Hydro Mask
AYUNCHEPro Care Deep Repairing Cream
FATIONGlucose Hydro Essence Toner 300ml
FATIONFATION Glucose Hydro Essence Toner 20ml (Trial Size)
Definition
7,9-dihydro-1H-purine-2,6,8(3H)-trione is an oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8. It has a role as a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is a tautomer of a 2,6-dihydroxy-7,9-dihydro-8H-purin-8-one, a 9H-purine-2,6,8-triol, a 7H-purine-2,6,8-triol, a 1H-purine-2,6,8-triol and a 5,7-dihydro-1H-purine-2,6,8(9H)-trione.
Source: PubChem
US FDA substance register · UNII 268B43MJ25 · registered name Uric Acid · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 尿酸: 本品は、次の化学式で表される複素環式化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 69-93-2
- EC No.EU chemical inventory number
- 200-720-7
- DTXSIDUS EPA chemical ID
- DTXSID3042508
- DTXCIDUS EPA compound ID
- DTXCID1022508
- IUPAC
- 7,9-Dihydro-1H-purine-2,6,8(3H)-trione
- Molecular formula
- C5H4N4O3
- Molecular weight
- 168.112 g/mol
Measured properties
- Appearance
- White odorless solid, [Merck Index] Beige powder, [Sigma-Aldrich MSDS] · Solid
- Melting point
- Greater than 300 °C · > 300 °C
- Solubility
- 60 mg/L (at 20 °C) · 0.06 mg/mL
- Dissociation constant
- 5.4
- pH
- 5.6
- Melting/freezing point
- 436 ℃
- Vapour pressure
- 5.8 ㎜Hg
- Relative density
- (1.855-1.893(20~20℃))
- Molecular weight
- 168.11
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- pH regulating agent1
- Softener and conditioner1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Evaluation of Serum Levels of Uric acid and Bilirubin in Iraqi Patients with Rosacea · 2024
- Wearable Biosensor Utilizing Chitosan Biopolymer for Uric Acid Monitoring · 2023
- A study of serum calcium and uric acid levels in Psoriasis · 2018
- The role of uric acid in metabolic syndrome in patients with psoriasis · 2017
- A new approach for noninvasive transdermal determination of blood uric acid levels · 2014
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese