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Ingredients

Ingredient Dictionary

URIC ACID

7,9-dihydro-1H-purine-2,6,8(3H)-trione is an oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 4 list it before the 1% line and 25 after it (usually 1% or less).

Products using this ingredient

12 of 29 confirmed · likeliest to carry enough first · See all 29

Definition

7,9-dihydro-1H-purine-2,6,8(3H)-trione is an oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8. It has a role as a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is a tautomer of a 2,6-dihydroxy-7,9-dihydro-8H-purin-8-one, a 9H-purine-2,6,8-triol, a 7H-purine-2,6,8-triol, a 1H-purine-2,6,8-triol and a 5,7-dihydro-1H-purine-2,6,8(9H)-trione.

Source: PubChem

US FDA substance register · UNII 268B43MJ25 · registered name Uric Acid · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONINGKeeps pH steadyBUFFERING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name 尿酸: 本品は、次の化学式で表される複素環式化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

URIC ACIDINCI우릭애씨드Korean label name (MFDS standard)1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-Synonym尿酸Japanese labelling name
CAS No.chemical registry number
69-93-2
EC No.EU chemical inventory number
200-720-7
DTXSIDUS EPA chemical ID
DTXSID3042508
DTXCIDUS EPA compound ID
DTXCID1022508
IUPAC
7,9-Dihydro-1H-purine-2,6,8(3H)-trione
Molecular formula
C5H4N4O3
Molecular weight
168.112 g/mol

Measured properties

Appearance
White odorless solid, [Merck Index] Beige powder, [Sigma-Aldrich MSDS] · Solid
Melting point
Greater than 300 °C · > 300 °C
Solubility
60 mg/L (at 20 °C) · 0.06 mg/mL
Dissociation constant
5.4
pH
5.6
Melting/freezing point
436 ℃
Vapour pressure
5.8 ㎜Hg
Relative density
(1.855-1.893(20~20℃))
Molecular weight
168.11

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • pH regulating agent1
  • Softener and conditioner1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 1 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across

Source: US EPA CompTox dashboard

Related literature

Linked databases 20