Uridine is a ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a betaN1-glycosidic bond.
Definition
Uridine is a ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a betaN1-glycosidic bond. It has a role as a drug metabolite, a human metabolite and a fundamental metabolite. It is functionally related to a uracil.
Source: PubChem
US FDA substance register · UNII WHI7HQ7H85 · registered name URIDINE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ウリジン: 本品は、次の化学式で表される複素環式化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 58-96-8
- EC No.EU chemical inventory number
- 200-407-5
- EC No.EU chemical inventory number
- 200-607-5
- DTXSIDUS EPA chemical ID
- DTXSID40891555
- DTXCIDUS EPA compound ID
- DTXCID001030648
- IUPAC
- Uridine
- Molecular formula
- C9H12N2O6
- Molecular weight
- 244.203 g/mol
Measured properties
- Appearance
- Solid, [Merck Index] White powder, [Alfa Aesar MSDS] · Solid
- Melting point
- 165 °C · 163 °C
- Solubility
- 34.9 [ug/mL] (The mean of the results at pH 7.4)
- Colour
- white
- Odour
- odourless
- Melting/freezing point
- 166.5 ℃
- n-Octanol/water partition coefficient (Kow)
- -1.98
- Molecular weight
- 244.21
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
- Humectant1
Source: US EPA CompTox dashboard
Related literature
- Application of the Combination of Uridine Monophosphate and Choline in Real Clinical Practice (Expert Recommendations for Practicing Physicians) · 2024
- Case report of sacituzumab govitecan-hziy-induced neutropenia in a patient with metastatic triple-negative breast cancer and a uridine diphosphate glucuronosyltransferase family 1 member A1 poor metabolizer genotype · 2021
- Thermodynamics, functional and structural characterization of inosine–uridine nucleoside hydrolase from Leishmania braziliensis · 2017
- Pharmacokinetics of Uridine Following Ocular, Oral and Intravenous Administration in Rabbits · 2013
- Local Treatment of Hand-Foot Syndrome with Uridine/Thymidine: In Vitro Appraisal on a Human Keratinocyte Cell Line HaCaT · 2012
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese