Ursodeoxycholic acid is a bile acid found in the bile of bears (Ursidae) as a conjugate with taurine.
Definition
US FDA substance register · UNII 724L30Y2QR · registered name Ursodiol · single chemical substance
Ursodeoxycholic acid is a bile acid found in the bile of bears (Ursidae) as a conjugate with taurine. Used therapeutically, it prevents the synthesis and absorption of cholesterol and can lead to the dissolution of gallstones. It has a role as a mouse metabolite and a human metabolite. It is a C24-steroid, a dihydroxy-5beta-cholanic acid and a bile acid. It is a conjugate acid of an ursodeoxycholate.
Source: PubChem
Ursodiol is the organic compound
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 128-13-2
- EC No.EU chemical inventory number
- 204-879-3
- DTXSIDUS EPA chemical ID
- DTXSID6023731
- DTXCIDUS EPA compound ID
- DTXCID003731
- IUPAC
- 3alpha,7beta-Dihydroxy-5beta-cholan-24-oic acid
- Molecular formula
- C24H40O4
- Molecular weight
- 392.58 g/mol
Measured properties
- Appearance
- Solid · solid
- Melting point
- 200-205 · 203 °C
- Solubility
- 0.02 mg/mL
- Melting/freezing point
- 203 ℃
- Molecular weight
- 392.57
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Humectant1
- Softener and conditioner1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- SkinIrr2
Skin Irritation · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
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- A Canine Model of Chronic Graft-vs.-Host Disease · 2016
Linked databases 15
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese