Ingredient Dictionary

VERATROLE

Veratrole is a dimethoxybenzene with the methoxy groups at ortho-positions.

Definition

Veratrole is a dimethoxybenzene with the methoxy groups at ortho-positions. It has a role as a plant metabolite.

Source: PubChem

US FDA substance register · UNII 61WJZ2Q41I · registered name Veratrole · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

VERATROLEINCIBenzene, 1,2-dimethoxy-Synonym

CAS No.chemical registry number: 91-16-7
EC No.EU chemical inventory number: 202-045-3
DTXSIDUS EPA chemical ID: DTXSID7047065
DTXCIDUS EPA compound ID: DTXCID5027065

IUPAC: 1,2-Dimethoxybenzene
Molecular formula: C8H10O2
Molecular weight: 138.166 g/mol

Measured properties

Appearance: solid
Melting/freezing point: 22.5 ℃
Initial boiling point and range: 206 ℃
Flash point: 87 ℃
Vapour pressure: 0.47 ㎜Hg
Water solubility: 7304 ㎎/ℓ
Relative density: 1.1004
n-Octanol/water partition coefficient (Kow): 1.6
Viscosity: 1.65 cP (at 53℃)
Molecular weight: 138.17

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance3
Flavouring and nutrient2
Intermediate1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 2 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 6 studies

Classification not possible
Skin Irritation · Screening
Classification not possible
Skin Sensitization · Screening
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) The study was based on a design adopted by ICCVAM and ECETOC (technical report No. 78 Skin sensitization testing: methodological considerations, Brussels, Dec 1999. OECD guideline 429.
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) (version 1992-07-17) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) (version 1992-07-31) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) (version 1992-07-31) according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) (Version 1987-02-24) according to
Classification not possible
Eye Irritation · Screening