定義
米国FDA 物質登録 · UNII QJH0DSQ3SG · 登録名 VIOLACEIN · 単一の化学物質
Violacein is a member of the class of hydroxyindoles resulting from the formal oxidative coupling between the 3-position of 1,3-dihydro-2H-indol-2-one and the 3-position of 1,3-dihydro-2H-pyrrol-2-one, which is substituted at the 5 position by a 5-hydroxy-1H-indol-3-yl group, where the newly-formed double bond has E configuration. It is a purple chromobacterial pigment that has antibacterial, antifungal, antiprotozoan, and anticancer properties. It has a role as an antibacterial agent, an antineoplastic agent, an antifungal agent, an apoptosis inducer and a bacterial metabolite. It is a member of pyrroles, a member of oxindoles, an olefinic compound and a member of hydroxyindoles. It is functionally related to a proviolacein.
出典: PubChem
化粧品での役割
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
別名・識別情報
- CAS No.化学物質登録番号
- 548-54-9
- DTXSID米国EPA化学物質番号
- DTXSID001028415
- DTXCID米国EPA化合物番号
- DTXCID401513985
- IUPAC
- (3E)-3-[5-(5-Hydroxy-1H-indol-3-yl)-2-oxo-1,2-dihydro-3H-pyrrol-3-ylidene]-1,3-dihydro-2H-indol-2-one
- 分子式
- C20H13N3O3
- 分子量
- 343.342 g/mol
製品が実際に使っている用途
米国EPAにこの成分を届け出た製品3件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。
- Biocide1
- Antioxidant1
- Dye1
出典: 米国EPA CompTox
関連文献
- Violacein: A Promising Bacterial Secondary Metabolite · 2022
- In silico Screening of Violacein as an epidermal growth factor receptor inhibitor · 2022
- Violacein: a natural antibacterial agent empowered by film-forming sprays for topical applications · 2025
- Genome sequencing and multifaceted taxonomic analysis of novel strains of violacein-producing bacteria and non-violacein-producing close relatives · 2023
- Comparative analysis of stability and biological activities of violacein and starch capped silver nanoparticles · 2017