Wogonin is a dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-8.
Definition
Wogonin is a dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-8. It has a role as an antineoplastic agent, an angiogenesis inhibitor, a cyclooxygenase 2 inhibitor and a plant metabolite. It is a monomethoxyflavone and a dihydroxyflavone. It is a conjugate acid of a wogonin(1-).
Source: PubChem
US FDA substance register · UNII POK93PO28W · registered name WOGONIN · single chemical substance
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 632-85-9
- DTXSIDUS EPA chemical ID
- DTXSID70212557
- DTXCIDUS EPA compound ID
- DTXCID00135048
- IUPAC
- 5,7-Dihydroxy-8-methoxy-2-phenyl-4H-1-benzopyran-4-one
- Molecular formula
- C16H12O5
- Molecular weight
- 284.267 g/mol
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Bleaching agent1
Source: US EPA CompTox dashboard
Related literature
- Wogonin as a potential therapeutic agent for psoriasis: Core target identification and validation · 2026
- Wogonin ameliorates the proliferation, inflammatory response, and pyroptosis in keratinocytes via NOD‐like receptor family pyrin domain containing 3/Caspase‐1/Gasdermin‐D pathway · 2024
- Topical Application of Wogonin Provides a Novel Treatment of Knee Osteoarthritis · 2020
- Wogonin suppresses proliferation and invasion of skin epithelioid carcinoma cells through Notch1. · 2020
- Wogonin inhibits the proliferation and invasion, and induces the apoptosis of HepG2 and Bel7402 HCC cells through NF‑κB/Bcl-2, EGFR and EGFR downstream ERK/AKT signaling. · 2016