Xanthohumol is a member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'.
定义
Xanthohumol is a member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'. Isolated from Humulus lupulus, it induces apoptosis in human malignant glioblastoma cells. It has a role as an antiviral agent, a metabolite, an antineoplastic agent, an EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor, an anti-HIV-1 agent and an apoptosis inducer. It is a member of chalcones, a polyphenol and an aromatic ether. It is a conjugate acid of a xanthohumol(1-).
来源: PubChem
美国FDA 物质登记 · UNII T4467YT1NT · 登记名称 XANTHOHUMOL · 单一化学物质
化妆品中的作用
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 6754-58-1
- DTXSID美国EPA化学品编号
- DTXSID00893171
- DTXCID美国EPA化合物编号
- DTXCID601323110
- IUPAC
- (2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
- 分子式
- C21H22O5
- 分子量
- 354.402 g/mol
实测物性
- 性状
- Solid
- 熔点
- 172 °C
这是对物质本身测得的数值,并非原料商品的规格。
来源: PubChem
产品实际使用的用途
相关文献
- A Novel Look at Mechanisms and Applications of Xanthohumol (XN) in Dermatology and Cosmetology · 2024
- Analytical Assessment of the Quality of Dietary Supplements and Cosmetic Products Containing Xanthohumol by Thin-Layer Chromatography Along with the Estimation of Its Antioxidant Potential · 2024
- The influence of UV irradiation on fish skin collagen films in the presence of xanthohumol and propanediol. · 2022
- The integrative bioinformatics approaches to predict the xanthohumol as anti-breast cancer molecule: Targeting cancer cells signaling PI3K and AKT kinase pathway · 2022
- Evaluation of the Antitumour and Antiproliferative Effect of Xanthohumol-Loaded PLGA Nanoparticles on Melanoma · 2021