Definition
US FDA substance register · UNII Y39HBC4LEH · registered name 2,3-Dimethylbenzenesulfonic acid · single chemical substance
Cosmetic roles
Safety & regulatory references
Korea’s toxic-substance GHS classification: Danger · H302 (category 4) · H290 (category 1) · H314 (category 1B)
Reviewed by CIR: Safety Assessment of Xylene Sulfonic Acid, Toluene Sulfonic Acid, and Alkyl Aryl Sulfonate Hydrotropes as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 25321-41-9
- EC No.EU chemical inventory number
- 246-839-8
- DTXSIDUS EPA chemical ID
- DTXSID4027860
Measured properties
- Appearance
- Liquid
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 17 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Surfactant (surface active agent)5
- Catalyst4
- Dispersing agent2
- Defoamer2
- Flotation agent2
- Intermediate1
- Solubility enhancer1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to EU Method B.6 (Skin Sensitisation) - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Category 8.3A (Category 1)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
Linked databases 15
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard
- US EPA DSSTox chemical database
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata