Zerumbone is a sesquiterpenoid and cyclic ketone that is (1E,4E,8E)-alpha-humulene which is substituted by an oxo group at the carbon atom attached to two double bonds.
Definition
Zerumbone is the organic compound that conforms to the formula:
Zerumbone is a sesquiterpenoid and cyclic ketone that is (1E,4E,8E)-alpha-humulene which is substituted by an oxo group at the carbon atom attached to two double bonds. It is obtained by steam distillation from a type of edible ginger, Zingiber zerumbet Smith, grown particularly in southeast Asia. It has a role as a glioma-associated oncogene inhibitor, an anti-inflammatory agent and a plant metabolite. It is a sesquiterpenoid and a cyclic ketone. It derives from a hydride of an alpha-humulene.
Source: PubChem
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ゼルンボン: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 471-05-6
- EC No.EU chemical inventory number
- 687-304-2
- DTXSIDUS EPA chemical ID
- DTXSID601318583
- DTXCIDUS EPA compound ID
- DTXCID501748389
- IUPAC
- (2E,6E,10E)-2,6,9,9-Tetramethylcycloundeca-2,6,10-trien-1-one
- Molecular formula
- C15H22O
- Molecular weight
- 218.34 g/mol
Related literature
- Zerumbone Induces Heme Oxygenase-1 Expression in Mouse Skin and Cultured Murine Epidermal Cells through Activation of Nrf2 · 2011
- Skin lightening properties of zerumbone cream: A placebo‐controlled study · 2024
- Zerumbone from Zingiber zerumbet (L.) Roscoe ex Sm. ameliorates atopic dermatitis by regulating the MAP kinase/NF-κB, Akt, and STAT pathways. · 2026
- Potential application of zerumbone in the prevention and therapy of chronic human diseases · 2019
- Antimicrobial activity of the crude extract, fractions and isolation of zerumbone from the rhizomes of Zingiber roseum · 2019