Definition
US FDA substance register · UNII TSZ9EY203A · registered name ZINC SILICATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Korea’s toxic-substance GHS classification: Warning · H400 (category 1) · H410 (category 1)
Reviewed by CIR: Amended Safety Assessment of Silicates as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 13597-65-4
- DTXSIDUS EPA chemical ID
- DTXSID8035976
- DTXCIDUS EPA compound ID
- DTXCID501851645
- IUPAC
- Dizinc silicate
- Molecular formula
- O4SiZn2
- Molecular weight
- 222.84 g/mol
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Intermediate2
- Deodorizer1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) Adopted July 22, 2010 according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) Council regulations (EC) No. 440/2008 method B.42. (amended in Commission Regulation (EU) No. 640/2012, adopted July 06, 2012). - Severe Irritation
eye irritation: in vitro / ex vivo · Screening · OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants) [before 26 July 2013] according to EU method B.47 (Bovine corneal opacity and permeability test method for identifying ocular corrosives and severe irritants) Commission Regulation (EU) No. 1152/2010 method B.47 (published in the Official Journal of the European Union L324, dated December 09, 2010). according to
Source: US EPA CompTox dashboard
Related literature
- Synthesis and characterization of ZnO nanorods-Zn2SiO4 nanoparticles-PMMA nanocomposites for UV-C protection · 2022
- Zinc Silicate-Loaded Microneedle Patch Reduces Reactive Oxygen Species Production and Enhances Collagen Synthesis for Ultraviolet B-Induced Skin Repair · 2025
- Spindle‐Like Zinc Silicate Nanoparticles Accelerating Innervated and Vascularized Skin Burn Wound Healing · 2022
- Design of a biofluid-absorbing bioactive sandwich-structured Zn–Si bioceramic composite wound dressing for hair follicle regeneration and skin burn wound healing · 2020
Linked databases 12
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- NIST Chemistry WebBook
- Tlooto literature search 2 3 4
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata