Docosanoic acid is a straight-chain, C22, long-chain saturated fatty acid.
How much products actually contain
1 products state the amountmedian 0.0025%
- under 0.01% 1
- 0.01–0.1% 0
- 0.1–1% 0
- 1% or more 0
Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.
Of the products containing it, 22 list it before the 1% line and 32 after it (usually 1% or less).
Products using this ingredient
12 of 54 confirmed · likeliest to carry enough first · See all 54
NoilyNOILYSKIN ALL-IN-ONE MILKY BUBBLE TONER0.0025% stated
Kiss MeHeavy Rotation Eyebrow Pencil (6 Colors)
M·A·CM·A·C Hyper Real Fresh Canvas Cream-To-Foam Cleanser - 1.0 fl oz
M·A·CM·A·C Hyper Real Fresh Canvas Cream-To-Foam Cleanser - 4.2 fl oz
TatchaTatcha The Brightening Eye Cream
CelladixTrouble Sebum Rebalancing RX 131 Ampoule 30ml
OclearienSkin Balance Cream
Peach & LilyPeach & Lily Retinal For All Renewing Serum
TRIMAYDual Firming & Lifting Cream
I'm FromI'm From Honey Glow Cream
tartetarte tartelette™ shadow stick
PHYSIOGELPhysiogel DMT Regenerative Cream 100ml
Definition
Docosanoic acid is a straight-chain, C22, long-chain saturated fatty acid. It has a role as a plant metabolite. It is a long-chain fatty acid and a straight-chain saturated fatty acid. It is a conjugate acid of a behenate.
Source: PubChem
US FDA substance register · UNII H390488X0A · registered name Behenic acid · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Final Report: Safety Assessment of Fatty Acids and Fatty Acid Salts as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ベヘン酸: 本品は、次の化学式で表される脂肪酸である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 112-85-6
- EC No.EU chemical inventory number
- 204-010-8
- DTXSIDUS EPA chemical ID
- DTXSID3026930
- DTXCIDUS EPA compound ID
- DTXCID306930
- IUPAC
- Docosanoic acid
- Molecular formula
- C22H44O2
- Molecular weight
- 340.592 g/mol
Measured properties
- Appearance
- Other Solid, Large Crystals, Liquid · White to cream or yellow solid, [CHEMINFO] White crystalline powder, [MSDSonline]
- Boiling point
- 306 °C at 60 mm Hg
- Melting point
- 79.95 °C · 81 °C
- Solubility
- 0.102 g are sol in 100 g of 90% ethanol at 17 °C, 0.218 g are sol in 100 ml of 91.5% ethanol at 25 °C, 0.116 g are sol in 100 ml of 86.2% ethanol at 25 °C, 0.011 g are sol in 100 ml of 63.07% ethanol at 25 °C, 0.1922 g are sol in 100 g of ether at 16 °C · Slightly soluble in water, ethanol, ethyl ether
- Density
- 0.8221 at 100 °C/4 °C
- Melting/freezing point
- 80 ℃
- Initial boiling point and range
- 306 ℃(60 mmHg)
- Flash point
- 176 ℃
- Upper/lower flammability or explosive limits
- - / - %
- Vapour pressure
- 0.0000000715 ㎜Hg ((25 ℃))
- Water solubility
- 0.00001294 ㎎/ℓ
- Relative density
- 0.8223 ((90 ℃))
- n-Octanol/water partition coefficient (Kow)
- 9.91
- Viscosity
- 12.8 cP (80 C)
- Molecular weight
- 340.59
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 32 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Emulsifier8
- Opacifer4
- Surfactant (surface active agent)4
- Lubricating agent4
- Cleaning agent2
- Solids separation (precipitating) agent, not other2
- Intermediate2
- Softener and conditioner2
3 other uses
- Processing aids not otherwise specified2
- Monomers1
- Fuel1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
- Structural color generation in lipid-based cosmetics: Lamellar nanosheets from skin-identical fatty acids. · 2025
- Inhibitory Effect of Moringa oleifera Seed Extract and Its Behenic Acid Component on Staphylococcus aureus Biofilm Formation · 2024
- Preparation and characterization of itraconazole loaded nanomicelles based on dextran–behenic acid for cutaneous leishmaniasis treatment · 2021
- The Effect of Vegetable Oil Composition on the Structural Properties of Oleogels Based on Behenyl Alcohol/Behenic Acid Oleogelator System. · 2021
- Effect of the ratio between behenyl alcohol and behenic acid on the oleogel properties. · 2019
Linked databases 21
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese