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Ingredients

Ingredient Dictionary

BHA

3-tert-butyl-4-hydroxyanisole is an aromatic ether that is 4-methoxyphenol in which one of the hydrogens ortho- to the phenolic hydroxy group is replaced by a tert-butyl group.

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 6 list it before the 1% line and 31 after it (usually 1% or less).

Products using this ingredient

12 of 37 confirmed · likeliest to carry enough first · See all 37

Definition

3-tert-butyl-4-hydroxyanisole is an aromatic ether that is 4-methoxyphenol in which one of the hydrogens ortho- to the phenolic hydroxy group is replaced by a tert-butyl group. It has a role as an antioxidant and a human xenobiotic metabolite. It is a member of phenols and an aromatic ether.

Source: PubChem

US FDA substance register · UNII REK4960K2U · registered name BUTYLATED HYDROXYANISOLE · mixture

Source: US FDA Unique Ingredient Identifier (UNII)

BHA is a mixture of isomers of tertiary butyl-substituted 4-methoxyphenols. It consists chiefly of 3-t-butyl-4-hydroxyanisole with lesser amounts of 2-t-butyl-4-hydroxyanisole. It conforms generally to the formula:

Cosmetic roles

Slows spoilage by oxygenANTIOXIDANTListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCE

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments - 2004/2005

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report: Safety Assessment of BHA as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name BHA: 本品は、4-メトキシフェノールに t-ブチル基が置換したものの混合物である。主に3-t-ブチル-4-ヒドロキシアニソールからなり、少量の2-t-ブチル-4-ヒドロキシアニソールを含み、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

BHAINCI비에이치에이Korean label name (MFDS standard)Phenol, (1,1-dimethylethyl)-4-methoxy-Synonym
CAS No.chemical registry number
25013-16-5
EC No.EU chemical inventory number
246-563-8
DTXSIDUS EPA chemical ID
DTXSID7020215
DTXCIDUS EPA compound ID
DTXCID701285159
Molecular formula
C11H16O2

What products actually use it for

What the 19 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Antioxidant8
  • Processing aids not otherwise specified2
  • Fragrance2
  • Deodorizer2
  • Flavouring and nutrient1
  • Biocide1
  • Filler1
  • Food preservative (EPA)1
1 other uses
  • Oxidizing agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 1 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 5 studies
  • Category 6.5B (Category 1)
    Skin Sensitization · Read Across
  • SkinIrr2
    Skin Irritation · QSAR Predicted
  • Category 1
    Skin Sensitization · Screening
  • Classification not possible
    Skin Irritation · Screening
  • Classification not possible
    Eye Irritation · Screening

Source: US EPA CompTox dashboard

Related literature

Linked databases 19