Ethylene glycol (ingested) can cause developmental toxicity according to The National Toxicology Program.
How much products actually contain
No product states its amount yet.
Of the products containing it, 3 list it before the 1% line and 3 after it (usually 1% or less).
Products using this ingredient
6 of 6 confirmed · likeliest to carry enough first
Scotch PorterScotch Porter Beard Gro Accelerator
DUFT&DOFTDUFT&DOFT Enriched Perfume Water Barrier Hand Cream Stockholm Rose 50ml
Acnes3-Second Calming Sun Cream 50ml
FOR:BEAUTBoost Curl Cream 150ml (Single/Special Set)
American CrewAmerican Crew FORMING PRE-STYLING SHAMPOO
MiseensceneNew Hello Cream Hair Dye
Definition
Ethylene glycol (ingested) can cause developmental toxicity according to The National Toxicology Program.
Source: PubChem
US FDA substance register · UNII FC72KVT52F · registered name Ethylene glycol · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name グリコール: 本品は、次の化学式で表される二価アルコールである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 107-21-1
- EC No.EU chemical inventory number
- 203-473-3
- DTXSIDUS EPA chemical ID
- DTXSID8020597
- DTXCIDUS EPA compound ID
- DTXCID40597
- IUPAC
- Ethane-1,2-diol
- Molecular formula
- C2H6O2
- Molecular weight
- 62.068 g/mol
Measured properties
- Appearance
- liquid
- Colour
- colourless
- Odour
- odourless
- Odour threshold
- 25 ppm
- pH
- 6~7.5
- Melting/freezing point
- -13 ℃
- Initial boiling point and range
- 198 ℃
- Flash point
- 111 ℃
- Upper/lower flammability or explosive limits
- 15.3 / 3.2 %
- Vapour pressure
- 7 ㎩(20℃)
- Water solubility
- 1000000 ㎎/ℓ(17.5℃)
- Vapour density
- 2.1
- Relative density
- 1.1
- n-Octanol/water partition coefficient (Kow)
- -1.36
- Auto-ignition temperature
- 398 ℃
- Decomposition temperature
- &, gt, 250 ℃
- Viscosity
- 16.1 cP(25℃)
- Molecular weight
- 62.07
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 223 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Freeze-thaw additive38
- Degradant/impurity (EPA)31
- Solvent21
- Stabilizing agent10
- Coalescing agent10
- Processing aids not otherwise specified9
- Viscosity modifier9
- Anti-freeze agent7
40 other uses
- Monomers6
- Surfactant (surface active agent)5
- Anti-adhesive/cohesive5
- Thickening agent5
- Chemical reaction regulator4
- Intermediate4
- Lubricating agent4
- Solubility enhancer4
- No specific technical function4
- Filler4
- Soil amendments3
- Fragrance2
- Fuel2
- Wetting agent (non-aqueous)2
- Demulsifier2
- Binder2
- Humectant2
- Plasticizer2
- Cleaning agent2
- Hydraulic fluids2
- Sealant (barrier)2
- Catalyst2
- Brightener1
- Refrigerants1
- Biocide1
- Corrosion inhibitor1
- Insulators1
- Defoamer1
- Propellants, non-motive (blowing agents)1
- Conductive agent1
- Emulsifier1
- Elasticizer1
- Reducing agent1
- Dye1
- Adhesion/cohesion promoter1
- Film former1
- Heat transferring agent1
- Pigment1
- Hardener1
- pH regulating agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 2 eye studies are on record.
The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- Category 2
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) Guinea Pig Maximization Test - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to EU Method B.6 (Skin Sensitisation) - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Category 2B
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Glycol Stearate and Glycol Stearate SE · 2023
- Ethylene Glycol and Other Glycols · 2019
- Ethylene Glycol Monoethyl Ether Acetate · 2019
- Glycol Ethers: Ethers of Propylene, Butylene Glycols, and Other Glycol Derivatives · 2012
- Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics · 2012
Linked databases 22
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR)
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese