How much products actually contain
No product states its amount yet.
Of the products containing it, 7 list it before the 1% line and 8 after it (usually 1% or less).
Products using this ingredient
12 of 12 confirmed · likeliest to carry enough first
EASYDEWDaewoong Pharmaceutical EASYDEW Dark Spot Ampoule 12ml
MuradMurad Renewing Eye Cream
DermalogicaDermalogica age reversal eye complex
Paula's ChoiceCLINICAL 0.3% Retinol Treatment
EASYDEWMela B Toning Ampoule Cushion Foundation
EASYDEWMela B Toning Ampoule Cushion Foundation Refill 15g
EASYDEWMela B Toning Ampoule Cushion Foundation 15g
HawthorneHawthorne Brightening Eye Cream
numbuzinNo.9 NAD+ BIO Lifting-sil Essence
numbuzinnumbuzin No.9 NAD+ BIO Lifting-sil Essence
EASYDEWMela B Toning UV Sun Serum 40ml, 2-Pack
EASYDEWDark Spot Care UV Protection Sun Serum
Definition
US FDA substance register · UNII 4T2GVA922X · registered name HESPERIDIN METHYLCHALCONE · single chemical substance
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ヘスペリジンメチルカルコン: 本品は、次の化学式で表されるヘスペリジン（＊）の誘導体である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 24292-52-2
- EC No.EU chemical inventory number
- 246-128-2
- DTXSIDUS EPA chemical ID
- DTXSID90885262
- DTXCIDUS EPA compound ID
- DTXCID401024653
- IUPAC
- 3-Hydroxy-4-[(2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoyl]-5-methoxyphenyl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
- Molecular formula
- C29H36O15
- Molecular weight
- 624.592 g/mol
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Antioxidant2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- SkinIrr2
Skin Irritation · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
- Efficacy of Venoactive Substances and Drugs in the Treatment of Chronic Venous Insufficiency and Varicose Veins: A Narrative Review · 2026
- Hesperidin methyl chalcone alleviates imiquimod-induced psoriasis in mice: effects alone and in combination with methotrexate · 2025
- Therapeutic potential of hesperidin methyl chalcone in the experimental treatment of cutaneous leishmaniasis · 2024
- Oral phytochemicals as photoprotectants in UVR exposed hairless mice: A study of hesperidin methyl chalcone, phloroglucinol, and syringic acid. · 2023
- Effects of dextran sulfate, 4-t-butylcyclohexanol, pongamia oil and hesperidin methyl chalcone on inflammatory and vascular responses implicated in rosacea · 2018
Linked databases 14
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata