METHYLPARABEN

Methylparaben is the ester of methyl alcohol and p-hydroxybenzoic acid. It conforms to the formula:

Methylparaben is a 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries. It has a role as an antifungal agent, a neuroprotective agent, an antimicrobial food preservative and a plant metabolite.

Source: PubChem

US FDA substance register · UNII A2I8C7HI9T · registered name Methylparaben · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Restricted

China · Japan · South Korea

Source: MFDS (Korea) cosmetic regulatory information

Argentina · Brazil

• Maximum concentration permitted at final product : (a) 0,4% (expresso como ácido) para cada substância considerada em forma individual. (b) 0,8% (expresso como ácido) para a soma das concentrações individuais de ácido 4-p-hidroxibenzóico, seus ésteres de metil e etil e seus sais contidos no produto.
• Other limitations and requirements : Prohibit: isopropylparaben, isobutylparaben, fenylparaben, benzylparaben, pentylparaben.

ASEAN

• Maximum authorised concentration in the finished cosmetic product : 0.4% (as acid) for single ester 0.8% (as acid) for mixtures of esters

Taiwan

• (a) 0.4%
• (b) 0.8%

European Union

• Maximum concentration in ready for use preparation : 0,4% (as acid) for single ester 0,8% (as acid) for mixtures of esters

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Restriction V/12 · Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Extended Opinion on the Safety Evaluation of Parabens; Opinion concerning Restrictions on Materials listed in annex VI of Directive 76/768/EEC on Cosmetic Products; Opinion on Parabens; Opinion on Parabens updated request for a scientific opinion on 'propyl-and butylparaben'; Opinion on Parabens, underarm cosmetics and breast cancer

Source: EU CosIng ingredient list

Reviewed by CIR: Final Amended Report on the Safety Assessment of Methylparaben, Ethylparaben, Propylparaben, Isopropylparaben, Butylparaben, Isobutylparaben and Benzylparaben as used in cosmetic products

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Amended Safety Assessment of Parabens as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Methylparaben, Ethylparaben, Propylparaben, and Butylparaben

Source: US Cosmetic Ingredient Review (CIR)