Butan-1-ol is a primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group.
How much products actually contain
No product states its amount yet.
Of the products containing it, 1,236 list it before the 1% line and 5 after it (usually 1% or less).
Products using this ingredient
12 of 1,240 confirmed · likeliest to carry enough first · See all 1,240
FOINDFOIND 001 VEGAN COMFORT NAIL HARDENER
FOINDFOIND 001 VEGAN TINTED NAIL HARDENER
Nails.INCNails.INC Better On Top Quick-Drying Top Coat - Glaze
Holo TacoHolo Taco Bonus Life
Holo TacoHolo Taco Wanderlust
R+CoR+Co OUTER SPACE Flexible Hairspray
R+CoR+Co OUTER SPACE Flexible Hairspray - Mini
Deborah LippmannDeborah Lippmann Gloss Protection Top Coat
Nails.INCNails.INC Break Repair Liquid Nail Patch Treatment
Nails.INCNails.INC Get Hard Hardening Base Coat
Nails.INCNails.INC Maniplex Hardening Bond Repair Nail Growth Treatment
Nails.INCNails.INC Mini Speedy 2 In 1 Base and Top Coat 5ml
Definition
Butan-1-ol is a primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It it produced in small amounts in humans by the gut microbes. It has a role as a protic solvent, a mouse metabolite and a human metabolite. It is a primary alcohol, a short-chain primary fatty alcohol and an alkyl alcohol.
Source: PubChem
US FDA substance register · UNII 8PJ61P6TS3 · registered name Butyl alcohol · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Final Report of the Addendum to the Safety Assessment of n-Butyl Alcohol as Used in Cosmetics
Reviewed by CIR: Final Report on the Safety Assessment of n-Butyl Alcohol
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ブタノール: 本品は、次の化学式で表される脂肪族アルコールである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 71-36-3
- EC No.EU chemical inventory number
- 200-751-6
- DTXSIDUS EPA chemical ID
- DTXSID1021740
- DTXCIDUS EPA compound ID
- DTXCID701740
- IUPAC
- Butan-1-ol
- Molecular formula
- C4H10O
- Molecular weight
- 74.123 g/mol
Measured properties
- Appearance
- N-butyl alcohol is a colorless liquid. Used in organic chemical synthesis, plasticizers, detergents, etc. · Liquid, CBI
- Odour
- HARSH FUSEL ODOR WITH BANANA · Odor similar to amyl alcohol
- Boiling point
- 243.9 °F at 760 mmHg (USCG, 1999) · 117.7 °C
- Melting point
- -129 °F (USCG, 1999) · -89.8 °C
- Solubility
- 9 % (NIOSH, 2024) · 63200 mg/L (at 25 °C)
- Colour
- colourless
- Melting/freezing point
- -90 ℃
- Initial boiling point and range
- 117 ℃
- Flash point
- 29.9 ℃
- Upper/lower flammability or explosive limits
- 11.3 / 1.4 %
- Vapour pressure
- 9.31 hPa(20℃)
- Vapour density
- 2.6
- Relative density
- 0.81 (g/cm3)
- n-Octanol/water partition coefficient (Kow)
- 1
- Auto-ignition temperature
- 345 ℃
- Viscosity
- 2.947 cP(20℃)
- Molecular weight
- 74.12
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 57 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent27
- Fragrance5
- Processing aids not otherwise specified3
- Intermediate2
- Chemical reaction regulator2
- Surfactant (surface active agent)2
- Flavouring and nutrient2
- Pigment2
9 other uses
- Dispersing agent2
- Plasticizer2
- Fuel2
- Conductive agent1
- Viscosity modifier1
- Defoamer1
- Cleaning agent1
- Monomers1
- Reducing agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
8 skin studies and 7 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 15 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Skin corrosion/irritation - Category 2
Skin Irritation · Screening - Skin Irrit. 2
Skin Irritation · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · equivalent or similar to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Category 2
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Category 6.3B (Category 3)
Skin Irritation · Read Across - Skin Irrit. 2
Skin Irritation · Authoritative - Serious eye damage/eye irritation - Category 2
Eye Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across - Eye Dam. 1
Eye Irritation · Authoritative - Eye Dam. 1
Eye Irritation · Screening - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Category 2A
Eye Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Quantitative Analysis and Molecular Docking Simulation of Flavonols from Eruca sativa Mill. and Their Effect on Skin Barrier Function · 2024
- Anti-aging and Antimicrobial Effects of the Stems and Roots of Sedum kamtschaticum in Cosmetic Production · 2023
- Geniposidic Acid from Eucommia ulmoides Oliver Staminate Flower Tea Mitigates Cellular Oxidative Stress via Activating AKT/NRF2 Signaling · 2022
- Siegesbeckiae Herba Extract and Chlorogenic Acid Ameliorate the Death of HaCaT Keratinocytes Exposed to Airborne Particulate Matter by Mitigating Oxidative Stress · 2021
- Inhibitory effects of Korean indigenous plants on tyrosinase and melanogenesis. · 2013
Linked databases 21
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese