サリチル酸

B

ランダム化試験1〜2件

C

対照のない試験・複合製品の試験

D

基礎研究や資料の記録のみ

アスピリンにアレルギーがある場合は使わないでください。

Salicylic acid is a monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves. It has a role as an antiinfective agent, an antifungal agent, a plant hormone, a keratolytic drug, an EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor, a plant metabolite and an algal metabolite. It is a conjugate acid of a salicylate.

出典: PubChem

米国FDA 物質登録 · UNII O414PZ4LPZ · 登録名 Salicylic Acid · 単一の化学物質

出典: 米国FDA 物質識別番号（UNII）

Salicylic Acid is the aromatic acid that conforms to the formula:

制限

イギリス · 韓国

許可された防腐剤

イギリス

出典: ASEAN 化粧品指令 · EU 化粧品規則 · カナダ 禁止・制限成分リスト · 韓国食薬処 化粧品規制情報 · 台湾FDA 化粧品成分 · 台湾FDA 化粧品規制 · 英国 化粧品規則 · 日本 化粧品基準

アルゼンチン · ブラジル

• Field of application and/or use : (a) hair products that are rinsed (b) Other products
• Maximum concentration permitted at final product : (a) 3% (b) 2%
• Other limitations and requirements : Should not be used in products in products for children under 3 years old, except for shampoos.
• Use conditions and warnings that must appear on the label : -For adult use products: "Do not use in children” - For products designed for children public: "Do not use in children under 3 years old".
• Maximum concentration permitted at final product : 0.5% (expressed as acid)
• Other limitations and requirements : Prohibited in products for children under 3 years of age, except for shampoos.
• Use conditions and warnings that must appear on the label : Products for use Adults: "Do not use in children" For products aimed at children: "Do not use in children under three years of age (except shampoo)"

ASEAN

• Field of application and/or use : (a) Rinse-off hair products (b) Other products except body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant (c) Body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant
• Maximum authorised concentration in the finished cosmetic product : (a) 3.0 % (b) 2.0% (c) 0.5%
• Other limitations and requirements : (a) (b) (c) Not to be used in preparations for children under 3 years of age. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products. For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product. These levels are inclusive of any use of salicylic acid. As a preservative, see Annex VI, Part 1, No 3
• Conditions of use and warning which must be printed on the labels : (a) (b) (c) Not to be used for children under three years of age
• Solely for products which might be used for children
• Maximum authorised concentration in the finished cosmetic product : Salicylic acid: 0,5 % (acid) Salicylic acid salts: 0,5 % (acid)
• Other limitations and requirements : Salicylic acid: Not to be used in products for children under 3 years of age. Not to be used in oral products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Salicylic acid salts: Not to be used in products for children under 3 years of age, except for shampoos.
• Conditions of use and warning which must be printed on the labels : Salicylic acid: Not to be used for children under 3 years of age Salicylic acid salts: Not to be used for children under 3 years of age

カナダ

• Maximum Concentration Permitted : 2%

台湾

• ※ 染髮產品之限量標準：係指該成分依產品使用說明書混合後之最高允許使用量。
• ※ 化粧品之外包裝或容器，應明顯標示本表所列成分之注意事項。因外包裝或容器表面積過小或其他特殊情形致不能標示者，應於標籤、仿單或以其他方式刊載之。
• ※ 本表所稱之口腔製劑，包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
• ※ 化粧品宣稱效能者，須符合化粧品標示宣傳廣告涉及虛偽誇大或醫療效能認定準則規定。
• 註：該成分作為防腐劑用途時，應參照化粧品防腐劑成分名稱及使用限制表之規定。倘非防腐劑用途者，業者可自行依據產品屬性，判斷是否需於產品外包裝標示其用途。惟倘產品因未刊載其用途，致生危害消費者身體、健康時，企業經營者應自負相關責任。
• 用途 : 使用限制
• 最大配合量 : 2%
• 除洗髮產品外，不得使用於三歲以下孩童之產品。

日本

• 100gあたりの最大配合量(Maximum amount of ingredient per 100 g) : 0.20(0.20 g)

中国

• 最大配合量 : (a) 2.0%
• (b) 3.0%

欧州連合

• Product Type, body parts : (a) Rinse-off hair products (b) Other products except body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant (c) Body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant
• Maximum concentration in ready for use preparation : (a) 3.0% (b) 2.0% (c) 0.5%
• Other : (a) (b) (c) Not to be used in preparations for children under 3 years of age. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products. For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product. These levels are inclusive of any use of salicylic acid.
• Wording of conditions of use and warnings : (a) (b) (c) Not to be used for children under three years of age
• Solely for products which might be used for children under 3 years of age.
• Maximum concentration in ready for use preparation : Salicylic acid: 0,5 % (acid) Salicylic acid salts: 0,5 % (acid)
• Other : Salicylic acid: Not to be used in products for children under 3 years of age. Not to be used in oral products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Salicylic acid salts: Not to be used in products for children under 3 years of age, except for shampoos.
• Wording of conditions of use and warnings : Salicylic acid: Not to be used for children under 3 years of age **Solely for products which might be used for children under 3 years of age. Salicylic acid salts: Not to be used for children under 3 years of age ***Solely for products which might be used for children under 3 years of age and which remain in prolonged contact with the skin.

韓国の有害物質GHS分類なし · 既存化学物質

出典: 韓国 有害物質GHS情報（環境公団）

EU化粧品規則 附属書III（制限物質） 第98項 · 最大濃度 (a) 3.0% (b) 2.0% (c) 0.5% · 適用 (a) Rinse-off hair products (b) Other products except body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant (c) Body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant

出典: EU 制限成分（附属書III）

Restriction III/98 V/3 · SCCS opinion: OPINION ON salicylic acid (CAS 69-72-7) Submission I

出典: EU CosIng 成分リスト

Reviewed by CIR: Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics

出典: 米国CIR 安全性評価

Reviewed by CIR: Final Report on the Safety Assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Isodecyl Salicylate, Magnesium Salicylate, MEA-Salicylate, Ethylhexyl Salicylate, Potassium Salicylate, Methyl Salicylate, Myristyl Salicylate, Sodium Salicylate, TEA-Salicylate, and Tridecyl Salicylate

出典: 米国CIR 安全性評価