How much products actually contain
No product states its amount yet.
Of the products containing it, 10 list it before the 1% line and 35 after it (usually 1% or less).
Products using this ingredient
12 of 44 confirmed · likeliest to carry enough first · See all 44
Dieux SkinDieux Skin Deliverance 3-in-1 Repair Serum
Banila CoPrime Primer Finish Powder 12g
SOME BY MISOME BY MI Truecica Aqua Calming Sun Cream 50ml
VerbVerb Ghost™ Exfoliating Scalp Nectar
TIRTIRMask Fit Red Cushion
Biome ActivatePerfect No.1 Cleansing Oil
Biome ActivateGentle No.1 Foam Cleanser
COSNORICOSNORI Blossom Tone-Up Cushion, Pink Beige SPF50+ PA+++
Shua IrehGlow Filter Sun Cream
AHCNatural Perfection Fresh Sun Stick
NACIFICFresh Herb Origin Toner
d'AlbaWhite Truffle Prime Intensive Serum
Definition
US FDA substance register · UNII 64L053FRFO · registered name SODIUM PALMITOYL PROLINE · single chemical substance
Cosmetic roles
Safety & regulatory references
Reviewed by CIR: Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name パルミトイルプロリンＮａ: 本品は、次の化学式で表されるアミノ酸誘導体である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 58725-33-0
- EC No.EU chemical inventory number
- 261-406-3
- DTXSIDUS EPA chemical ID
- DTXSID80974255
- DTXCIDUS EPA compound ID
- DTXCID301401686
- IUPAC
- Sodium 1-hexadecanoyl-5-oxo-L-prolinate
- Molecular formula
- C21H36NNaO4
- Molecular weight
- 389.512 g/mol
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.6 (Skin Sensitisation) - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation) - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Linked databases 12
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata